In 1959, Horn became administrative assistant to Secretary of Labor James P. Mitchell. In 1960, he went to work for then U.S. Senator Thomas Kuchel as a legislative assistant and served in that capacity until 1966, when he left to become a Senior fellow at the Brookings Institution. Horn played a major role in the 1964 presidential campaign of Nelson Rockefeller in California. He also served as Vice Chairman of the U.S. Civil Rights Commission from 1969 to 1980 and as a member of the National Institute of Corrections from 1972 until 1988.
University president
Horn was President of California State University Long Beach from 1970 until 1988 when he stepped down to run for Congress. As President of CSULB, Horn reformed the university's graduation and general education requirements to emphasize learning skills, cultural literacy, and interdisciplinary education, as well as creating the first university and human resource opportunities course requirement in the United States. Horn also gained passage of legislation allowing California's senior citizens to take courses for reduced fees on all 23 campuses of the California State University. Horn established one of America's first programs for women returning to college. He also created the CSULB Disabled Resources Center, which served as a model to institutions across the United States. Horn led the university through 11 major construction projects, including the North Campus Center and buildings for Engineering/Computer Science, Social Science/Public Affairs, and Student Services Administration.
Congressional service
Horn first ran for Congress in 1988 in a race to succeed Republican Dan Lungren but lost the primary to conservative Dana Rohrabacher. After the 1991 reapportionment, his home in Long Beach was drawn into the neighboring 38th district, then held by veteran Democratic incumbent Glenn M. Anderson. When Anderson announced his retirement in 1992, Horn jumped into the race to succeed him. He narrowly won an 8-way Republican primary before beating Anderson's stepson, then Long Beach city councilman Evan Anderson Braude, in the general election. A moderate Republican, Horn won his Democratic-leaning district with relative ease four more times. In 1994 he rode the Republican tide to an easy victory over a weak opponent. In 1996, his reelection was eased when he became the only Republican west of the Mississippi River to be endorsed by the Sierra Club; In 1998 he once again bested his 1994 foe despite a strong year for Democrats statewide in California. Only in 2000 did he have a close race, beating Democrat Gerrie Schipske by less than 1 percent. After the 2001 reapportionment, Democrats in the California legislature made this already Democratic-leaning district even more so. Horn subsequently announced his retirement and did not seek reelection in 2002. He did, however, give a surprise endorsement to Democrat Hector De La Torre, who ran to succeed Horn in the re-drawn seat and finished second to Linda T. Sanchez in the Democratic primary. In 2003, Project on Government Oversight, a government watchdog group, awarded Horn with its first ever Good Government Award for his contributions to government transparency and oversight, particularly his advocacy for public access to government information.