List of vaccine ingredients


This list of vaccine ingredients indicates the culture media used in the production of common vaccines and the excipients they contain, as published by the United States Centers for Disease Control and Prevention and Food and Drug Administration. Vaccine ingredients and production in other nations are substantially the same. Also listed are substances used in the manufacturing process.
To read the prescribing information for each individual vaccine, see
VaccineCulture mediaExcipients
Adenovirus vaccineDulbecco's Modified Eagle Medium, human diploid fibroblast cell culture Acetone, alcohol, anhydrous lactose, castor oil, cellulose acetate phthalate, dextrose, D-fructose, D-mannose, FD&C Yellow #6 aluminum lake dye, fetal bovine serum, human serum albumin, magnesium stearate, micro crystalline cellulose, plasdone C, Polacrilin potassium, potassium phosphate, sodium bicarbonate, sucrose
Anthrax vaccine Puziss–Wright medium 1095, synthetic or semisyntheticAluminum hydroxide, amino acids, benzethonium chloride, formaldehyde, inorganic salts and sugars, vitamins
BCG Synthetic or semisyntheticAsparagine, citric acid, lactose, glycerin, iron ammonium citrate, magnesium sulfate, potassium phosphate
DTaP Cohen–Wheeler or Stainer–Scholte media, synthetic or semisyntheticAluminum phosphate, formaldehyde, Glutaraldehyde, 2-phenoxyethanol
DTaP Cohen–Wheeler or Stainer–Scholte media, Lathan medium derived from bovine casein, Linggoud–Fenton medium derived from bovine extract, synthetic or semisyntheticAluminum hydroxide, bovine extract, formaldehyde, glutaraldhyde, polysorbate 80
DTaP Cohen–Wheeler or Stainer–Scholte media, synthetic or semisyntheticAluminum potassium sulfate, ammonium sulfate, bovine extract, formaldehyde, gelatin, peptone, polysorbate 80, sodium phosphate, thimerosal
DTaP-Hib Synthetic or semisyntheticAluminum potassium sulfate, ammonium sulfate, bovine extract, formaldehyde or formalin, gelatin, polysorbate 80, sucrose, thimerosal
DTaP-IPV Vero cell culture, synthetic or semisyntheticAluminum hydroxide, calf serum, formaldehyde, glutaraldehyde, lactalbumin hydrolysate, neomycin sulfate, polymyxin B, polysorbate 80
DTaP-HepB-IPV Bovine protein, Lathan medium derived from bovine casein, Linggoud–Fenton medium derived from bovine extract, Vero cell culture, synthetic or semisyntheticAluminum hydroxide, aluminum phosphate, calf serum, lactalbumin hydrolysate, formaldehyde, glutaraldhyde, neomycin sulfate, polymyxin B, polysorbate 80, yeast protein
DTaP-IPV-Hib Synthetic or semisyntheticAluminum phosphate, bovine serum albumin, formaldehyde, glutaraldehyde, MRC-5 cellular protein, neomycin, polymyxin B sulfate, polysorbate 80, 2-phenoxyethanol
DT vaccine Synthetic or semisyntheticAluminum potassium sulfate, bovine extract, formaldehyde, thimerosal
DT vaccine Synthetic or semisyntheticAluminum hydroxide, formaldehyde or formalin
Hib vaccine Synthetic or semisyntheticAmmonium sulfate, formaldehyde, sucrose
Hib vaccine Synthetic or semisyntheticAluminum hydroxyphosphate sulfate
Hib vaccine SemisyntheticFormaldehyde, lactose
Hib-HepB Synthetic or semisynthetic, yeast or yeast extractAmorphous aluminum hydroxyphosphate sulfate, amino acids, dextrose, formaldehyde, hemin chloride, mineral salts, nicotinamide adenine dinucleotide, potassium aluminum sulfate, sodium borate, soy peptone, yeast protein
Hepatitis A vaccine Human diploid tissue culture Aluminum hydroxide, amino acid supplement, formalin, MRC-5 cellular protein, neomycin sulfate, phosphate buffers, polysorbate 20
Hepatitis A vaccine Human diploid tissue culture Amorphous aluminum hydroxyphosphate sulfate, bovine albumin or serum, formaldehyde, MRC-5 cellular protein, sodium borate
Hepatitis B vaccine Yeast or yeast extractAluminum hydroxide, phosphate buffers, yeast protein
Hepatitis B vaccine Yeast or yeast extractAmorphous aluminum hydroxyphosphate sulfate, amino acids, dextrose, formaldehyde, mineral salts, potassium aluminum sulfate, soy peptone, yeast protein
HepA-HepB vaccine Human diploid tissue culture, yeast or yeast extractAluminum hydroxide, aluminum phosphate, amino acids, formalin, MRC-5 cells, neomycin sulfate, phosphate buffers, polysorbate 20, yeast protein
Human papillomavirus Trichoplusia ni cellsAluminum hydroxide, amino acids, lipids, mineral salts, sodium dihydrogen phosphate dehydrate, type 16 viral protein L1, type 18 viral protein L1, vitamins
Human papillomavirus Yeast or yeast extractAmino acids, amorphous aluminum hydroxyphosphate sulfate, carbohydrates, L-histidine, mineral salts, polysorbate 80, sodium borate, vitamins, yeast protein
Influenza vaccine Chicken embryoBeta-propiolactone, calcium chloride, dibasic sodium phosphate, egg protein, monobasic potassium phosphate, monobasic sodium phosphate, neomycin sulfate, polymyxin B, potassium chloride, sodium taurodeoxychoalate, thimerosal
Influenza vaccine Chicken embryoEgg proteins, formaldehyde, polysorbate 80, cetyltrimethylammonium bromide, neomycin sulfate, kanamycin
Influenza vaccine Chicken embryoSqualene, polysorbate 80, sorbitan trioleate, sodium citrate dehydrate, citric acid monohydrate, neomycin, kanamycin, barium, egg proteins, CTAB, formaldehyde
Influenza vaccine Chicken embryoFormaldehyde, octoxynol-10, α-tocopheryl hydrogen succinate, polysorbate 80, hydrocortisone, gentamicin sulfate, ovalbumin, sodium deoxycholate, sucrose, phosphate buffer
Influenza vaccine insect cell line Monobasic sodium phosphate, dibasic sodium phosphate, polysorbate 20, baculovirus and host cell proteins, baculovirus and cellular DNA, Triton X-100, lipids, vitamins, amino acids, mineral salts
Influenza vaccine Madin Darby Canine Kidney cell proteinMadin Darby Canine Kidney cell protein, MDCK cell DNA, polysorbate 80, cetyltrimethlyammonium bromide, β-propiolactone, phosphate buffer
Influenza vaccine Chicken embryoFormaldehyde, á-tocopheryl hydrogen succinate, polysorbate 80, sodium deoxycholate, thimerosal, ovalbumin
Influenza vaccine Chicken embryoBeta-propiolactone, egg protein, neomycin, nonylphenol ethoxylate, polymyxin, thimerosal, thimerosal
Influenza vaccine Chicken embryoEgg protein, formaldehyde, gelatin, octylphenol ethoxylate, sodium phosphate, thimerosal
Influenza vaccine Chicken kidney cells, chicken embryoArginine, dibasic potassium phosphate, egg protein, ethylenediaminetetraacetic acid, gentamicin sulfate, hydrolyzed porcine gelatin, monobasic potassium phosphate, monosodium glutamate, sucrose
Japanese encephalitis vaccine Mouse brain cultureFormaldehyde or formalin, gelatin, mouse serum protein, polysorbate 80, thimerosal
Japanese encephalitis vaccine Vero cell cultureAluminum hydroxide, bovine serum albumin, formaldehyde, protamine sulfate, sodium metabisulphite
Meningococcal vaccine Modified Mueller–Miller medium, Mueller–Hinton agar, Watson–Scherp mediumFormaldehyde, phosphate buffers
Meningococcal vaccine Watson–Scherp media, Mueller–Hinton agarLactose, thimerosal
Meningococcal vaccine Franz complete mediumAmino acids, formaldehyde, yeast extract
MMR vaccine Human diploid tissue culture, Medium 199Amino acids, fetal bovine serum, glutamate, hydrolyzed gelatin, neomycin, recombinant human serum albumin, sodium phosphate, sorbitol, sucrose, vitamins
MMRV vaccine Human diploid tissue cultures, Medium 199Bovine calf serum, dibasic potassium phosphate, dibasic sodium phosphate, human albumin, human serum albumin, hydrolyzed gelatin, monobasic potassium phosphate, monosodium L-glutamate, MRC-5 cellular protein, neomycin, sodium bicarbonate, sorbitol, sucrose, potassium chloride
Pneumococcal vaccine Bovine proteinPhenol
Pneumococcal vaccine Soy peptone brothAluminum phosphate, ammonium sulfate, casamino acid, polysorbate 80, succinate buffer, yeast
Polio vaccine Vero cell culture, Medium 199Calf serum protein, formaldehyde, neomycin, 2-phenoxyethanol, polymyxin B, streptomycin
Polio vaccine Human diploid tissue culture sodium chloride
Rabies vaccine Human diploid tissue culture Albumin, MRC-5 cells, neomycin sulfate, phenol
Rabies vaccine Rhesus fetal lung tissue culture, chicken embryoAmphotericin B, beta-propiolactone, chicken protein, chlortetracycline, human serum albumin, neomycin, ovalbumin, polygeline, potassium glutamate
Rotavirus vaccine Vero cell culturefetal bovine serum, sodium citrate, sodium phosphate monobasic monohydrate, sodium hydroxide, sucrose, polysorbate 80
Rotavirus vaccine Dulbecco's Modified Eagle Medium Amino acids, calcium carbonate, dextran, sorbitol, sucrose, vitamins, xanthan
Td vaccine Mueller–Miller medium, synthetic or semisyntheticAluminum potassium sulfate, bovine muscle tissue, formaldehyde, peptone, thimerosal
Td vaccine Modified Mueller's media, synthetic or semisyntheticAluminum phosphate, ammonium phosphate, bovine extracts, formaldehyde, thimerosal
Tdap vaccine Mueller's growth medium, Mueller–Miller casamino acidmedium, synthetic or semisyntheticAluminum phosphate, ammonium sulfate, formaldehyde, glutaraldehyde, 2-phenoxyethanol
Tdap vaccine Fenton media with bovine casein, Lathan medium derived from bovine casein, Linggoud–Fenton medium derived from bovine extract, Stainer–Scholte liquid medium, synthetic or semisyntheticAluminum hydroxide, bovine extract, formaldehyde, glutaraldehyde, polysorbate 80
Typhoid vaccine Synthetic or semisyntheticDisodium phosphate, monosodium phosphate, phenol, polydimethylsiloxane, hexadecyltrimethylammonium bromide
Typhoid vaccine Amino acids, ascorbic acid, casein, dextrose, galactose, lactose, sucrose, yeast extract
Vaccinia Vero cell cultureGlycerin, human serum albumin, mannitol, neomycin, phenol, polymyxin B
Varicella vaccine Human diploid tissue cultures Dibasic sodium phosphate, ethylenediamine tetra acetic acid sodium, fetal bovine serum, gelatin, glutamate, monobasic potassium phosphate, monobasic sodium phosphate, monosodium L-glutamate, MRC-5 DNA and cellular protein, neomycin, phosphate, potassium chloride, sucrose
[Yellow fever vaccine Chicken embryoEgg protein, gelatin, sorbitol
Zoster vaccine Human diploid tissue cultures Bovine calf serum, dibasic sodium phosphate, hydrolyzed porcine gelatin, monosodium L-glutamate, MRC-5 DNA and cellular protein, monobasic potassium phosphate, neomycin, potassium chloride, sucrose