The building is constructed of stone and surrounds two quadrangles. The smaller Outer Quadrangle to the north consists of: the outer gate ; the brewhouse ; from the 15th century, the guest wing, kitchen ; the porter's lodge and the three-storey Beaufort Tower of c. 1450. This has three niches above the arch, one of which still contains the weathered statue of Cardinal Beaufort, who was Bishop of Winchester, and the tower and spaces above the porter's lodge used to be the Master's lodging. Passing beneath the tower, the Inner Quadrangle is reached. The north range includes the 14th-century Brethren's Hall, entered via a flight of steps in a stone porch. There is a timber screen with gallery above, within which is also a splendid timber roof, arch braced; a central hearth and a dais where the Master dined with the Brethren in the main part of the hall; and a wooden staircase leading to the Master's rooms in the south-east corner. The main set of two-storeyed lodgings are on the north-west and west sides of the quadrangle; these house the 25 inmates and are notable for the tall, regularly spaced chimneys and doorways, each leading to four sets of apartments. There used to be a corresponding range on the south side joined to the church, but this was demolished in 1789. The eastern or infirmary range is occupied by an ambulatory. The 12th-century and 13th-century church in the south-east corner is more like a miniature cathedral than a typical almshouse chapel. The building is stone-vaulted throughout, with transepts and a central tower. The walls are over a metre thick, made from stone from Caen, Dorset, and the Isle of Wight as well as local flint. The roof is lead. The building is in Transitional Norman/Gothic style. Started in 1135, the chancel was the first part, built two bays deep with aisles. This is typically Norman, with round-headed windows and much chevron ornament. But the main arches in the arcade and beneath the central tower are slightly pointed in the Gothic manner. The three-bay aisled nave and transepts continue the style. Between 1383 and 1385, a large tracery window was inserted in the west front, and the clerestory windows in the nave were enlarged and a north porch added. Several medieval encaustic tiles survive on the floor. There are also traces of medieval wall paintings. The stained glass is mainly 19th century. The font came from the nearby St Faith's Church, which was demolished in 1507.
Charitable work
The Hospital still provides accommodation for a total of 25 elderly men, known as "The Brothers", under the care of "The Master". They belong to either of two charitable foundations: those belonging to the Order of the Hospital of St Cross wear black trencher hats and black robes with a silver badge in the shape of a Jerusalem cross, while those belonging to the Order of Noble Poverty wear claret trencher hats and claret robes with a silver cardinal's badge in memory of Cardinal Beaufort. They are often referred to as the "Black Brothers" and the "Red Brothers". Brothers must be single, widowed or divorced, and over 60 years of age. Preference is given to those in most need. They are expected to wear their robes and attend daily morning prayers in the Church. The Hospital continues an ancient tradition in the "Wayfarer's Dole", which consists of a small horn cup of ale and a piece of bread. The dole was started by a Cluniac monk and can be obtained by anyone who asks at the Porter's Lodge.
Media
The Hospital was used in the filming of The Day of the Triffids, and in the BBC adaptation of Wolf Hall. It was also featured on Songs of Praise.
Francis North, Earl of Guilford, son of a previous Bishop of Winchester, was Rector of St. Cross from 1829, and the long lasting enquiries into the large revenue that he received as such formed the inspiration for the novelThe Warden by Anthony Trollope.