CGP-35348

CGP-35348 is a compound used in scientific research which acts as an antagonist at GABA_B receptors.
CGP-35348 was ineffective up to 100 μM to antagonize the inhibitory release of GABA elicited by baclofen, doing it selective as GABA_B heteroreceptor antagonist.
Moreover, CGP-35348 was about threefold less potent to antagonize gamma-hydroxybutyrate and gamma-butyrolactone than baclofen and SKF-97,541.

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