During the years of the Greek War of Independence and while the conflicts was still raging in the region of Epirus, Ioannina, a city that was renowned for its cultural and educational background, and which had been a major center of the Greek Enlightenment, was falling into a short-term decay. At this point, five Zosimas brothers who had migrated to Russia and become successful merchants, decided to make a significant contribution to their homeland, sponsoring the foundation of a new educational institution. The Zosimaia School was founded in 1828 and initially functioned as a four-class school. The Schools Committee of Ioannina, an organization responsible of the management of the city’s educational institution, had the full responsibility of the Zosimaia’s management, with the financial aid of the Zosimas family.
Anastasios Sakellarios' administration, 1833-1862
In 1833 Anastasios Sakellarios from Zagori, a former student of Athanasios Psalidas - a major intellectual of the Greek Enlightenment and Ali Pasha’s advisor - became director of the Zosimaia. In 1840 three more classes were added in the school’s educational program. With Sakellarios’ administration, the Zosimaia became one of the most significant Greek-language schools of the Ottoman world. The majority of the students were from Epirus, but there were also many from Greek communities throughout the Ottoman Empire, e.g. from Eastern Rumelia. There were also transfers of students from other significant schools like the Phanar Greek Orthodox College in Constantinople. Additionally, a number of Turks and Albanians also attended Zosimaia, some of whom became leading personalities in their countries. The number of students reached 400 during the Sakellarios administration. Most of the graduates of Zosimaia either continued their studies, mostly in the University of Athens, or became teachers in one of the Greek schools in Balkan Peninsula. In 1860, due to the school's high prestige the school, the University of Athens allowed the entrance of Zosmaia graduates without any examinations. However, in 1862 Sakellarios resigned as a result of disagreements with other school officials of Ioannina.
Spyridon Manaris, from Sidirokastro, also professor of University of Athens
Georgios Soriritadis
Dimitrios Konstas
Antonis Travlantonis
The teachers were highly educated, with significant contribution to the cultural and educational activity of that time, like, for instance, Panagiotis Aravantinos, who wrote a great number of books on folklore and linguistics.