Lhamo's name means "goddess of song", a name given to her by a Buddhist monk. Lhamo left Tibet in 1989 to make a pilgrimage to Dharamsala. She was inspired to reach out to the world through her music. She moved to Australia in 1993, then to New York City in 2000. Lhamo's Australian debut album, Tibetan Prayer, produced by John Prior, won the ARIA Music Awards for best folk/world/traditional music release in 1995. The success of that record led to her signing with Peter Gabriel's Real World label. Her first record for the label, Tibet, Tibet, mainly features a cappella renditions of original compositions—authentic Tibetan Buddhist prayers and songs. Her next recording, Coming Home, was a collaboration with producer Hector Zazou, showcasing her voice and also featuring chanting by Tibetan monks, a wide range of mostly modern Western instruments and the benefits of multi-track recording which enabled Lhamo's voice to be layered repeatedly. According to the Times Herald Record, Lhamo has toured extensively in at least 70 countries, singing a combination of her own songs and traditional Buddhist chants and mantras. She has performed and recorded with a number of other artists, including Natalie Merchant, Peter Gabriel, Annie Lennox, Billy Corgan, and Bono. Lhamo's recordings have been used in the film Seven Years in Tibet and many Tibetan documentaries. She has performed at venues such as London's Royal Festival Hall, New York City's Carnegie Hall, and Berlin's Philharmonic Hall. She has also performed at the Lilith Fair festival and toured as a part of the WOMAD world music festivals. Lhamo's album Ama was released in April 2006 and was produced by Iranian-American musician Jamshied Sharifi. Featured artists include Annie Lennox on the song Fade Away and Joy Askew on the song Tara. In November 2007, Lhamo accompanied a site-specific dance work called "Walking The Line" by American choreographer Bill T. Jones at the Louvre Museum in Paris. The performance, which also featured solo percussion by Florent Jodelet, took place in a 300-foot space stretching from Michelangelo's statute The Dying Slave to the foot of the staircase leading to the sculpture Winged Victory of Samothrace. Lhamo's fifth album, Tayatha was released in June 2013 by Cantaloupe Music. On this album she collaborated with Russian pianist Anton Batagov. Lhamo's work with mentally ill and homeless people was covered by Newsweek.