The history of XEPE begins in August 1987, when Guillermo Dionisio Salas Vargas was selected by the Mexican government from among 19 applicants to operate a station on 1600 kHz. The call sign assigned at that time was XETCT-AM. By the time a concession was issued in 1994, the station had the call sign XEKTT-AM. In 1999, XEKTT was sold to Carlos de Jesús Quiñones Armendáriz, who in turn sold the station to Media Sports de México, S.A. de C.V. In the late 1990s and early 2000s, both the frequency and call sign changed, the former on several occasions. XEKTT unsuccessfully experimented with a move to a lower frequency. It abruptly moved to 550 kHz, which caused interference concerns for US stations. XEKTT was prompted to move to 560, but that did not remediate the interference and instead prompted action by US broadcasters who sought to revoke XEKTT's authorization to receive programming from across the border. In 2004, the SCT authorized the station to move to 1700 kHz, and in February 2005, the call sign was changed to XEPE-AM. XEPE was on the air in the spring of 2005 and used to supplement sister XEPRS in its coverage of San Diego Padres games. That August, XEPE added a business talk format under the branding "Cash 1700". On August 1, 2007, XEPE switched to a talk radio format, while keeping some business talk programs, such as financial talk show hostRay Lucia. Conservative syndicated talk shows from Michael Reagan and Dennis Miller were also on the schedule. After progressive talk station 1360 KLSD switched to a sports format, XEPE tried adding some liberal-leaning shows including one locally hosted by . The syndicated The Lionel Show was carried during overnight hours. In late 2009, XEPE became a partner to sister station XEPRS 1090. XEPRS was enjoying success as San Diego's top sports radio station, and XEPE began running some of the games and sports shows that XEPRS couldn't carry due to other commitments. On October 6, 2010, the station became an affiliate of ESPN Radio as ESPN 1700. In 2017, the station's daytime lineup began to carry a block of financial talk shows under the banner Your Business, Your Life. On December 12, 2018, the station's ESPN Radio programming, as well as that of sister station XHPRS-FM, was taken off-air due to a payment dispute between the station's ownership and Broadcast Company of the Americas. The over-the-air transmitter carried a simulcast of XESDD-AM until February 3, 2020, when the station began running the Heraldo Radio news-talk network from Mexico City.