Muthesius studied at the Berlin School of Arts from 1979 to 1984. He was a student of, whose designs influenced him. Muthesius' first artistic stay abroad led him to the Accademia di Belle Arti in Florence in 1982–83. His work there focused on the city's architecture. Based on many sketches, Muthesius created his first works in Indian ink, watercolor, tempera and oil. In 1982, he made the Brandenburg Gate in his home city of Berlin a motif in his works. These works demonstrate that Muthesius employs design through reduction, laying down the foundation of his present painting style. He received a working scholarship to the in 1987, and a series of Salzburg pictures dates to this time. In 1988 he visited New York Cityfor the first time, and has returned regularly ever since. In New York, Muthesius sketched soaring room perspectives and architectural highlights, particularly of the World Trade Center. In the aftermath of the September 11 attacks, he has been creating work relating to Ground Zero. When he received a working scholarship from the Berlin Senate in 1989, he continued using the Brandenburg Gate—the intersection of East and West—as his central motif. Muthesius' first series of "cross pictures" and "skull pictures" date to 1991 and 1992, and he has continued them until the present. He began to develop the technique of pittura oscura in 1992. These are multi-layered pictures which give the effect of depth, combining photography and painting: Muthesius creates a painting, derived from a sketch. It is then positioned in a public room and photographed. The photograph is painted over, and again reproduced. The Star series of large-format images was created in 1995. The subject of the Star and Cross series is violence in the past and present. Stars of David, beaten in with an axe and a chainsaw, explore the expulsion of the Jewish communities over the centuries as a reminder of the need for respect. In the Cross pictures, Muthesius dissolves the static cross and creates an impression of movement. The crosses were applied with bitumen and oil on a large-format support made of wood. Muthesius has focused to monochrome images in gold, such as the Golden Fields and Der Himmel unter Berlin, since 2002. From this, he developed a "broken gold" technique. The support, decorated with gold leaf, is then partially destroyed and scratched on the surface. This illustrates brittleness and vulnerability in time. Muthesius is inspired by the concrete forms in a room, which he outlines, paints, photographs, paints over, further processes, installs and places in new contexts. He intends to bring the observer into a conflict of perception which might alter their perspectives and views. Muthesius' starting point is an object whose core he reveals with a variety of techniques and reductions in several processes.
Analysis
According to, "The Skull pictures by Muthesius directly refer back to life 'In the serious ossuary' ... "a source of life arose from death. wrote about Brandenburg Gates: wrote about Star: Thomas A. Baltrock wrote about Cross: wrote about Golden Fields: Christoph Tannert wrote about Pittura Oscura: