Vesicle-associated membrane protein

• VAMP1 and VAMP2 proteins known as synaptobrevins are expressed in brain and are constituents of the synaptic vesicles, where they participate in neurotransmitter release.
• VAMP3 is ubiquitously expressed and participates in regulated and constitutive exocytosis as a constituent of secretory granules and secretory vesicles.
• VAMP5 and VAMP7 participate in constitutive exocytosis.
• * VAMP5 is a constituent of secretory vesicles, myotubes and tubulovesicular structures.
• * VAMP7 is found both in secretory granules and endosomes.
• VAMP8 participates in endocytosis and is found in early endosomes. VAMP8 also participates the regulated exocytosis in pancreatic acinar cells.
• VAMP4 is involved in transport from the Golgi.