The event was the first one as part of the promotion's five year contract with ESPN and the first to be broadcast on the network's digital streaming platform ESPN+. It generated 525,000 new subscribers to the service on the day of the event alone. A UFC Flyweight Championship bout between 2008 Olympic gold medalist in freestyle wrestling and current champion Henry Cejudo and current two-time UFC Bantamweight Champion T.J. Dillashaw headlined this event. If successful, Dillashaw would become the third man to be champion in two divisions simultaneously and fourth fighter overall, as well as the seventh person overall to win a title in different divisions. This was the fifth time in UFC history that champions in different divisions fought for the same title, following UFC 94, UFC 205, UFC 226 and UFC 232. According to sources, the promotion is expected to dissolve the flyweight division at some point within 2019. The pairing was initially expected to take place at UFC 233 a week later, but was moved on December 5. A women's flyweight bout between Rachael Ostovich and Paige VanZant was originally canceled on November 20 due to Ostovich being assaulted by her husband, resulting in a broken orbital bone. However after getting a second opinion from a doctor, though, Ostovich got the green light to stay in the bout. After announcing that former NFL player Greg Hardy would make his UFC debut at this event, the decision to put him on the same card as Ostovich was met with backlash by many people as Hardy was found guilty of assaulting an ex-girlfriend, and sentenced to 18 months probation as well as being suspended for 10 games by the NFL. The charges and suspension were later dropped after the victim failed to appear in court to testify, but Hardy's arrest and trial were the focus of considerable controversy. UFC president Dana White later claimed that Ostovich was "totally cool" with Hardy on the same card as her. A women's flyweight bout between KSW Women's Flyweight Champion and promotional newcomer Ariane Lipski and Joanne Calderwood was initially scheduled for UFC 233. However, it was reported on December 2 that the bout had been rescheduled for this event instead. As a result of the cancellation of UFC 233, a flyweight bout between former UFC Flyweight Championship challenger Joseph Benavidez and Deiveson Figueiredo was briefly linked to this event. However the following day, the promotion clarified plans indicating that the pairing was off and that Benavidez would be an alternate for the headliner bout in the event that either Cejudo or Dillashaw would be forced from the main event. Later it was announced that despite still being an alternate, Benavidez would face Dustin Ortiz in a rematch of his unanimous decision win at in November 2014. A bantamweight bout between Thomas Almeida and Cory Sandhagen was briefly linked to the event. However on December 22, it was announced that Sandhagen would face John Lineker in the event instead. On January 10, Lineker was forced to withdraw from the bout due to a rib injury. He was replaced by promotional newcomer Mario Bautista. Ion Cuțelaba was expected to face former UFC Light Heavyweight Championship challenger Glover Teixeira at this event. However on January 10, it was reported that Cuțelaba was forced out of the bout due to injury. He was replaced by Karl Roberson. Randy Brown was expected to face Chance Rencountre, but pulled out in the week leading up to the event. Dwight Grant was soon announced as his replacement, but it was later reported that he was unable to be cleared to fight due to an "eye issue". Promotional newcomer Kyle Stewart was then announced as Rencountre's new opponent.
Results
Bonus awards
The following fighters were awarded $50,000 bonuses:
Fight of the Night: Donald Cerrone vs. Alexander Hernandez
Performance of the Night: Henry Cejudo and Donald Cerrone
Suspension
On March 20, it was announced that Dillashaw was suspended one-year due to a failed drug test in relation to this event and therefore he decided to vacate his title. He initially received a one year suspension by the New York State Athletic Commission retroactive to the event's date. On April 9, Dillashaw accepted a two-year suspension by USADA, retroactive to January 19, as it was revealed he tested positive to erythropoietin in a fight night test.
