Tuscumbia was laid out in 1837. The community's name most likely is a transfer from Tuscumbia, Alabama. A post office called Tuscumbia has been in operation since 1837.
As of the census of 2010, there were 203 people, 55 households, and 38 families living in the village. The population density was. There were 70 housing units at an average density of. The racial makeup of the village was 93.6% White, 3.9% African American, 2.0% Native American, and 0.5% from other races. Hispanic or Latino of any race were 5.9% of the population. There were 55 households of which 34.5% had children under the age of 18 living with them, 47.3% were married couplesliving together, 12.7% had a female householder with no husband present, 9.1% had a male householder with no wife present, and 30.9% were non-families. 25.5% of all households were made up of individuals and 9.1% had someone living alone who was 65 years of age or older. The average household size was 2.56 and the average family size was 2.97. The median age in the village was 36.7 years. 18.2% of residents were under the age of 18; 11.3% were between the ages of 18 and 24; 36.1% were from 25 to 44; 28.1% were from 45 to 64; and 6.4% were 65 years of age or older. The gender makeup of the village was 65.0% male and 35.0% female.
2000 census
As of the census of 2000, there were 218 people, 57 households, and 40 families living in the town. The population density was 617.2 people per square mile. There were 72 housing units at an average density of 203.9 per square mile. The racial makeup of the town was 95.41% White, 1.83% African American, 0.46% Native American, 0.92% Asian, and 1.38% from two or more races. Hispanic or Latino of any race were 1.38% of the population. There were 57 households out of which 29.8% had children under the age of 18 living with them, 54.4% were married couples living together, 14.0% had a female householder with no husband present, and 28.1% were non-families. 24.6% of all households were made up of individuals and 15.8% had someone living alone who was 65 years of age or older. The average household size was 2.35 and the average family size was 2.68. In the town the population was spread out with 15.1% under the age of 18, 20.2% from 18 to 24, 31.7% from 25 to 44, 22.5% from 45 to 64, and 10.6% who were 65 years of age or older. The median age was 35 years. For every 100 females, there were 159.5 males. For every 100 females age 18 and over, there were 156.9 males. The median income for a household in the town was $19,375, and the median income for a family was $26,875. Males had a median income of $15,341 versus $16,000 for females. The per capita income for the town was $8,117. About 12.0% of families and 19.3% of the population were below the poverty line, including 35.7% of those under the age of eighteen and 36.8% of those sixty five or over.
