Transporter Classification Database

Classification

1. Channels">Ion channel">Channels and pores

1.A α-type channels

• 1.A.1 Voltage-gated ion channel superfamily
• 1.A.2 Inward-rectifier K⁺ channel family
• 1.A.3 Ryanodine-inositol-1,4,5-trisphosphate receptor Ca²⁺ channel family
• 1.A.4 Transient receptor potential Ca²⁺ channel family
• 1.A.5 Polycystin cation channel family
• 1.A.6 Epithelial Na⁺ channel family
• 1.A.7 ATP-gated P2X receptor cation channel family
• 1.A.8 Major intrinsic protein superfamily
• 1.A.9 Neurotransmitter receptor, Cys loop, ligand-gated ion channel family
• 1.A.10 Glutamate-gated ion channel family of neurotransmitter receptors
• 1.A.11 Ammonium channel transporter family
• 1.A.12 Intracellular chloride channel family
• 1.A.13 Epithelial chloride channel family
• 1.A.14 Testis-enhanced gene transfer family
• 1.A.15 Nonselective cation channel-2 family
• 1.A.16 Formate-nitrite transporter family
• 1.A.17 Calcium-dependent chloride channel family
• 1.A.18 Chloroplast envelope anion-channel-forming Tic110 family
• 1.A.19 Type A influenza virus matrix-2 channel family
• 1.A.20 BCL2/Adenovirus E1B-interacting protein 3 family
• 1.A.21 Bcl-2 family
• 1.A.22 Large-conductance mechanosensitive ion channel
• 1.A.23 Small-conductance mechanosensitive ion channel
• 1.A.24 Gap-junction-forming connexin family
• 1.A.25 Gap-junction-forming innexin family
• 1.A.26 Mg²⁺ transporter-E family
• 1.A.27 Phospholemman family
• 1.A.28 Urea transporter family
• 1.A.29 Urea/amide channel family
• 1.A.30 H⁺- or Na⁺-translocating bacterial MotAB flagellar motor/ExbBD outer-membrane transport energizer superfamily
• 1.A.31 Annexin family
• 1.A.32 Type B influenza virus NB channel family
• 1.A.33 Cation-channel-forming heat shock protein 70 family
• 1.A.34 Bacillus gap junction-like channel-forming complex family
• 1.A.35 CorA metal ion transporter family
• 1.A.36 Intracellular chloride channel family
• 1.A.37 CD20 Ca²⁺ channel family
• 1.A.38 Golgi pH regulator family
• 1.A.39 Type C influenza virus CM2 channel family
• 1.A.40 Human immunodeficiency virus type I Vpu channel family
• 1.A.41 Avian reovirus p10 Vvroporin family
• 1.A.42 HIV viral protein R family
• 1.A.43 Camphor resistance or fluoride exporter family
• 1.A.44 Pore-forming tail Tip pb2 protein of phage T5 family
• 1.A.45 Phage P22 injectisome family
• 1.A.46 Anion channel-forming bestrophin family
• 1.A.47 Nucleotide-sensitive anion-selective channel, ICln family
• 1.A.48 Anion channel Tweety family
• 1.A.49 Human coronavirus ns12.9 viroporin family
• 1.A.50 Phospholamban family
• 1.A.51 The Voltage-gated Proton Channel Family
• 1.A.52 The Ca²⁺ Release-activated Ca²⁺ Channel Family
• 1.A.53 The Hepatitis C Virus P7 Viroporin Cation-selective Channel Family
• 1.A.54 The Presenilin ER Ca²⁺ Leak Channel Family
• 1.A.55 The Synaptic Vesicle-Associated Ca²⁺ Channel, Flower Family
• 1.A.56 The Copper Transporter Family
• 1.A.57 The Human SARS Coronavirus Viroporin
• 1.A.58 The Type B Influenza Virus Matrix Protein 2 Family
• 1.A.59 The Bursal Disease Virus Pore-Forming Peptide, Pep46 Family
• 1.A.60 The Mammalian Reovirus Pre-forming Peptide, Mu-1 Family
• 1.A.61 The Insect Nodavirus Channel-forming Chain F Family
• 1.A.62 The Homotrimeric Cation Channel Family
• 1.A.63 The Ignicoccus Outer Membrane α-helical Porin Family
• 1.A.65 The Coronavirus Viroporin E Protein Family
• 1.A.66 The Pardaxin Family
• 1.A.67 The Membrane Mg²⁺ Transporter Family
• 1.A.68 The Viral Small Hydrophobic Viroporin Family
• 1.A.69 The Heteromeric Odorant Receptor Channel Family
• 1.A.70 The Molecule Against Microbes A Family
• 1.A.71 The Brain Acid-soluble Protein Channel Family
• 1.A.72 The Mer Superfamily
• 1.A.73 The Colicin Lysis Protein Family
• 1.A.74 The Mitsugumin 23 Family
• 1.A.75 The Mechanical Nociceptor, Piezo Family
• 1.A.76 The Magnesium Transporter1 Family
• 1.A.77 The Mg²⁺/Ca²⁺ Uniporter Family
• 1.A.78 The K⁺-selective Channel in Endosomes and Lysosomes Family
• 1.A.79 The Cholesterol Uptake Protein or Double Stranded RNA Uptake Family
• 1.A.80 The NS4a Viroporin Family
• 1.A.81 The Low Affinity Ca²⁺ Channel Family
• 1.A.82 The Hair Cell Mechanotransduction Channel Family
• 1.A.83 The SV40 Virus Viroporin VP2 Family
• 1.A.84 The Calcium Homeostasis Modulator Ca²⁺ Channel Family
• 1.A.85 The Poliovirus 2B Viroporin Family
• 1.A.86 The Human Papilloma Virus type 16 L2 Viroporin Family
• 1.A.87 The Mechanosensitive Calcium Channel Family
• 1.A.88 The Fungal Potassium Channel Family
• 1.A.89 The Human Coronavirus 229E Viroporin Family
• 1.A.90 The Human Metapneumovirus Viroporin Family
• 1.A.91 The Cytoadherence-linked Asexual Protein 3.2 of Plasmodium falciparum Family
• 1.A.92 The Reovirus Viroporin VP10 Family
• 1.A.93 The Bluetongue Virus Non-Structural Protein 3 Viroporin Family
• 1.A.94 The Rotavirus Non-structural Glycoprotein 4 Viroporin Family
• 1.A.95 The Ephemerovirus Viroporin Family
• 1.A.96 The Human Polyoma Virus Viroporin Family
• 1.A.97 The Human Papillomavirus type 16 E5 Viroporin Family
• 1.A.98 Human T-Lymphotropic Virus 1 P13 protein Family
• 1.A.99 The Infectious Bronchitis Virus Envelope Small Membrane Protein E Family
• 1.A.100 The Rhabdoviridae Putative Viroporin, U5 Family
• 1.A.101 The Peroxisomal Pore-forming Pex11 Family
• 1.A.102 Influenza A viroporin PB1-F2 Family
• 1.A.103 The Simian Virus 5 SH Family
• 1.A.104 The Proposed Flagellar Biosynthesis Na⁺ Channel, FlaH Family
• 1.A.105 The Mixed Lineage Kinase Domain-like Family
• 1.A.106 The Calcium Load-activated Calcium Channel Family
• 1.A.107 The Pore-forming Globin Family

  1.B. β-Barrel porins">Porin (protein)">β-Barrel porins and other outer membrane proteins

• 1.B.1 General bacterial porin family
• 1.B.2 Chlamydial porin family
• 1.B.3 Sugar porin family
• 1.B.4 Brucella-Rhizobium porin family
• 1.B.5 Pseudomonas OprP porin family
• 1.B.6 OmpA-OmpF porin family
• 1.B.7 Rhodobacter PorCa porin family
• 1.B.8 Mitochondrial and plastid porin family
• 1.B.9 FadL outer membrane protein family
• 1.B.10 Nucleoside-specific channel-forming outer membrane porin family
• 1.B.11 Outer membrane fimbrial usher porin family
• 1.B.12 Autotransporter-1 family
• 1.B.13 Alginate export porin family
• 1.B.14 Outer membrane receptor family
• 1.B.15 Raffinose porin family
• 1.B.16 Short chain amide and urea porin family
• 1.B.17 Outer membrane factor family
• 1.B.18 Outer membrane auxiliary protein family
• 1.B.19 Glucose-selective OprB porin family
• 1.B.20 Two-partner secretion family
• 1.B.21 OmpG porin family
• 1.B.22 Outer bacterial membrane secretin family
• 1.B.23 Cyanobacterial porin family
• 1.B.24 Mycobacterial porin
• 1.B.25 Outer membrane porin family
• 1.B.26 Cyclodextrin porin family
• 1.B.31 Campylobacter jejuni major outer membrane oorin family
• 1.B.32 Fusobacterial outer membrane porin family
• 1.B.33 Outer membrane protein insertion porin family
• 1.B.34 Corynebacterial porins
• 1.B.35 Oligogalacturonate-specific porin family
• 1.B.39 Bacterial porin, OmpW family
• 1.B.42 Outer membrane lipopolysaccharide export porin family
• 1.B.43 Coxiella porin P1 family
• 1.B.44 Probable protein translocating porphyromonas gingivalis porin family
• 1.B.49 Anaplasma P44 porin family
• 1.B.48 Curli-like transporters
• 1.B.54 Intimin/Invasin or Autotransporter-3 family
• 1.B.55 Poly-acetyl-D-glucosamine porin family
• 1.B.57 Legionella major-outer membrane protein family
• 1.B.60 Omp50 porin family
• 1.B.61 Delta-proteobacterial porin family
• 1.B.62 Putative bacterial porin family
• 1.B.66 Putative beta-barrel porin-2 family
• 1.B.67 Putative beta barrel porin-4 family
• 1.B.68 Putative beta barrel porin-5 superfamily
• 1.B.70 Outer membrane channel family
• 1.B.71 Proteobacterial/verrucomicrobial porin family
• 1.B.72 Protochlamydial outer membrane porin family
• 1.B.73 Capsule biogenesis/assembly family
• 1.B.78 DUF3374 electron transport-associated porin family

  1.C [Pore-forming toxin]s (proteins and peptides)

• 1.C.3 α-Hemolysin family
• 1.C.4 Aerolysin family
• 1.C.5 ε-toxin family
• 1.C.11 RTX-toxin superfamily
• 1.C.12 Membrane attack complex/perforin superfamily
• 1.C.13 Leukocidin family
• 1.C.14 Cytohemolysin family
• 1.C.39 Thiol-activated cholesterol-dependent cytolysin family
• 1.C.43 Lysenin family
• 1.C.56 Pseudomonas syringae HrpZ cation channel family
• 1.C.57 Clostridial cytotoxin family
• 1.C.74 Snake cytotoxin family
• 1.C.97 Pleurotolysin pore-forming family

  1.D Non-ribosomally synthesized channels

• 1.D.1 The Gramicidin A Channel Family
• 1.D.2 The Channel-forming Syringomycin Family
• 1.D.3 The Channel-Forming Syringopeptin Family
• 1.D.4 The Tolaasin Channel-forming Family
• 1.D.5 The Alamethicin or Peptaibol Antibiotic Channel-forming Family
• 1.D.6 The Complexed Poly 3-Hydroxybutyrate Ca²⁺ Channel Family
• 1.D.7 The Beticolin Family
• 1.D.8 The Saponin Family
• 1.D.9 The Polyglutamine Ion Channel Family
• 1.D.10 The Ceramide-forming Channel Family
• 1.D.11 The Surfactin Family
• 1.D.12 The Beauvericin Family
• 1.D.13 DNA-delivery Amphipathic Peptide Antibiotics
• 1.D.14 The Synthetic Leu/Ser Amphipathic Channel-forming Peptide Family
• 1.D.15 The Daptomycin Family
• 1.D.16 The Synthetic Amphipathic Pore-forming Heptapeptide Family
• 1.D.17 Combinatorially-designed, Pore-forming, β-sheet Peptide Family
• 1.D.18 The Pore-forming Guanosine-Bile Acid Conjugate Family
• 1.D.19 Ca²⁺ Channel-forming Drug, Digitoxin Family
• 1.D.20 The Pore-forming Polyene Macrolide Antibiotic/fungal Agent Family
• 1.D.21 The Lipid Nanopore Family
• 1.D.22 The Proton-Translocating Carotenoid Pigment, Zeaxanthin Family
• 1.D.23 Phenylene Ethynylene Pore-forming Antimicrobial Family
• 1.D.24 The Marine Sponge Polytheonamide B Family
• 1.D.25 The Arylamine Foldamer Family
• 1.D.26 The Dihydrodehydrodiconiferyl alcohol 9'-O-β-D-glucoside Family
• 1.D.27 The Thiourea isosteres Family
• 1.D.28 The Lipopeptaibol Family
• 1.D.29 The Macrocyclic Oligocholate Family
• 1.D.30 The Artificial Hydrazide-appended pillararene Channels Family
• 1.D.31 The Amphotericin B Family
• 1.D.32 The Pore-forming Novicidin Family
• 1.D.33 The Channel-forming Polytheonamide B Family
• 1.D.34 The Channel-forming Oligoester Bolaamphiphiles
• 1.D.35 The Pore-forming cyclic Lipodepsipeptide Family
• 1.D.36 The Oligobornene Ion Channel Family
• 1.D.37 The Hibicuslide C Family
• 1.D.38 The Cyclic Peptide Nanotube Family
• 1.D.39 The Light-controlled Azobenzene-based Amphiphilic Molecular Ion Channel Family
• 1.D.40 The Protein-induced Lipid Toroidal Pore Family
• 1.D.41 The Sprotetonate-type Ionophore Family
• 1.D.42 The Phe-Arg Tripeptide-PillarArene Channel Family
• 1.D.43 The Triazole-tailored Guanosine Dinucleoside Channel Family
• 1.D.44 The Synthetic Ion Channel with Redox-active Ferrocene Family
• 1.D.45 The Sonoporation and Electroporation Membrane Pore Family
• 1.D.46 The DNA Nanopore Family
• 1.D.47 The Pore-forming Synthetic Cyclic Peptide Family
• 1.D.48 The Pore-forming Syringomycin E Family
• 1.D.49 The Transmembrane Carotenoid Radical Channel Family
• 1.D.50 The Amphiphilic bis-Catechol Anion Transporter Family
• 1.D.51 The Protein Nanopore Family
• 1.D.52 The Aromatic Oligoamide Macrocycle Nanopore Family
• 1.D.53 The alpha, gamma-Peptide Nanotube Family
• 1.D.54 The potassium-selective Hexyl-Benzoureido-15-Crown-5-Ether Ion Channel Family
• 1.D.55 The Porphyrin-based Nanopore Family
• 1.D.56 The Alpha-Aminoisobutyrate Oligomeric Nanopore Family
• 1.D.57 The Lipid Electro-Pore Family
• 1.D.58 The Anion Transporting Prodigiosene Family
• 1.D.59 The Anion Transporting Perenosin Family
• 1.D.60 The Alpha,Gamma-Cyclic Peptide Family
• 1.D.61 The Anionophoric 2,6-BisPyridine Family
• 1.D.62 The Bis-Triazolyl DiGuanosine Derivative Channel-forming Family
• 1.D.63 The Peptide-based Nanopore Family
• 1.D.64 The Carbon Nanotube Family
• 1.D.65 The Pore-forming Amphidinol Family
• 1.D.66 The Helical Macromolecule Nanopore Family
• 1.D.67 The Crown Ether-modified Helical Peptide Ion Channel Family
• 1.D.68 The Pore-forming Pleuronic Block Polymer Family
• 1.D.69 The Conical Nanopore Family
• 1.D.70 The Metallic Nanopore Family
• 1.D.71 The Synthetic TP359 Peptide Family
• 1.D.72 The Chloride Carrier Triazine-based Tripodal Receptor Family
• 1.D.73 The Mesoporous Silica Nanopore Family
• 1.D.74 The Stimulus-responsive Synthetic Rigid p-Octiphenyl Stave Pore Family

  1.E [Holin]s

1.F [Vesicle fusion] pores

• 1.F.1 The Synaptosomal Vesicle Fusion Pore Family
• 1.F.2 The Octameric Exocyst Family

  1.G Viral fusion">Viral protein#Viral envelope">Viral fusion pores

• 1.G.1 The Viral Pore-forming Membrane Fusion Protein-1 Family
• 1.G.2 The Viral Pore-forming Membrane Fusion Protein-2 Family
• 1.G.3 The Viral Pore-forming Membrane Fusion Protein-3 Family
• 1.G.4 The Viral Pore-forming Membrane Fusion Protein-4 Family
• 1.G.5 The Viral Pore-forming Membrane Fusion Protein-5 Family
• 1.G.6 The Hepadnaviral S Fusion Protein Family
• 1.G.7 The Reovirus FAST Fusion Protein Family
• 1.G.8 The Arenavirus Fusion Protein Family
• 1.G.9 The Syncytin Family
• 1.G.10 The Herpes Simplex Virus Membrane Fusion Complex Family
• 1.G.11 Poxvirus Cell Entry Protein Complex Family
• 1.G.12 The Avian Leukosis Virus gp95 Fusion Protein Family
• 1.G.13 The Orthoreovirus Fusion-associated Small Transmembrane Family
• 1.G.14 The Influenza Virus Hemagglutinin/Fusion Pore-forming Protein Family
• 1.G.15 The Autographa californica Nuclear Polyhedrosis Virus Major Envelope Glycoprotein GP64 Family
• 1.G.16 The Human Immunodeficiency Virus Type 1 Fusion Peptide Family
• 1.G.17 The Bovine Leukemia Virus Envelop Glycoprotein Family
• 1.G.18 The SARS-CoV Fusion Peptide in the Spike Glycoprotein Precursor Family
• 1.G.19 The Rotavirus Pore-forming Membrane Fusion Complex Family
• 1.G.20 The Hantavirus Gc Envelope Fusion Glycoprotein Family
• 1.G.21 The Epstein Barr Virus Gp42 Family
• 1.G.22 The Cytomegalovirus Glycoprotein gO Family

  1.H [Paracellular channel]s

• 1.H.1 The Claudin Tight Junction Family
• 1.H.2 The Invertebrate PMP22-Claudin Family

  1.I [Membrane-bound channel]s

• 1.I.1 Nuclear pore complex family, including karyopherins
• 1.I.2 Plant plasmodesmata family

  2. Electrochemical potential-driven transporters

2.A Porters ([uniporter]s, [symporter]s, [antiporter]s)

• 2.A.1 Major Facilitator superfamily, see also Lactose permease, Phosphate permease and Glucose transporter
• 2.A.2
• 2.A.3 The Amino Acid-Polyamine-Organocation Family
• 2.A.4 Cation diffusion facilitator Family
• 2.A.5 Zinc -Iron Permease Family
• 2.A.6 Resistance-Nodulation-Cell Division Superfamily, see also SecDF protein-export membrane protein
• 2.A.7 The Drug/Metabolite Transporter Superfamily
• 2.A.8 The Gluconate:H⁺ Symporter Family
• 2.A.9 The Membrane Protein Insertase Family
• 2.A.10 The 2-Keto-3-Deoxygluconate Transporter Family
• 2.A.11 The Citrate-Mg²⁺:H⁺ Citrate-Ca²⁺:H⁺ Symporter Family
• 2.A.12
• 2.A.13 The C4-Dicarboxylate Uptake Family
• 2.A.14 Lactate Permease Family
• 2.A.15 The Betaine/Carnitine/Choline Transporter Family
• 2.A.16 Tellurite-resistance/Dicarboxylate Transporter Family
• 2.A.17 Proton-dependent Oligopeptide Transporter Family
• 2.A.18 The Amino Acid/Auxin Permease Family
• 2.A.19 The Ca²⁺:Cation Antiporter Family
• 2.A.20 The Inorganic Phosphate Transporter Family
• 2.A.21 Solute:Sodium Symporter Family
• 2.A.22 The Neurotransmitter:Sodium Symporter Family
• 2.A.23 The Dicarboxylate/Amino Acid:Cation Symporter Family
• 2.A.24 The 2-Hydroxycarboxylate Transporter Family
• 2.A.25 Alanine or Glycine:Cation Symporter Family
• 2.A.26 The Branched Chain Amino Acid:Cation Symporter Family
• 2.A.27 The Glutamate:Na⁺ Symporter Family
• 2.A.28 Family
• 2.A.29 Mitochondrial carrier Family
• 2.A.30 Cation-Chloride Cotransporter Family
• 2.A.31 Anion Exchanger Family
• 2.A.32 The Silicon Transporter Family
• 2.A.33 NhaA Na⁺:H⁺ Antiporter Family
• 2.A.34 The NhaB Na⁺:H⁺ Antiporter Family
• 2.A.35 The NhaC Na⁺:H⁺ Antiporter Family
• 2.A.36 Family
• 2.A.37 Family
• 2.A.38 K⁺ Transporter Family
• 2.A.39 Nucleobase:Cation Symporter-1 Family
• 2.A.40 Nucleobase:Cation Symporter-2 Family
• 2.A.41 The Concentrative Nucleoside Transporter Family
• 2.A.42 The Hydroxy/Aromatic Amino Acid Permease Family
• 2.A.43 The Lysosomal Cystine Transporter Family
• 2.A.45 Arsenite-Antimonite Efflux Family
• 2.A.46 The Benzoate:H⁺ Symporter Family
• 2.A.47 Divalent Anion:Na⁺ Symporter Family
• 2.A.48 The Reduced Folate Carrier Family
• 2.A.49 Chloride Carrier/Channel Family
• 2.A.50 The Glycerol Uptake Family
• 2.A.51 The Chromate Ion Transporter Family
• 2.A.52 The Ni²⁺-Co²⁺ Transporter Family
• 2.A.53 Sulfate permease Family
• 2.A.54 The Mitochondrial Tricarboxylate Carrier Family
• 2.A.55 The Metal Ion Transporter Family
• 2.A.56 The Tripartite ATP-independent Periplasmic Transporter Family
• 2.A.57 The Equilibrative Nucleoside Transporter Family
• 2.A.58 The Phosphate:Na⁺ Symporter Family
• 2.A.59 The Arsenical Resistance-3 Family
• 2.A.60 Organo Anion Transporter Family
• 2.A.61 The C4-dicarboxylate Uptake C Family
• 2.A.62 The NhaD Na⁺:H⁺ Antiporter Family
• 2.A.63 The Monovalent Cation :Proton Antiporter-3 Family
• 2.A.64 Twin Arginine Targeting Family
• 2.A.65 The Bilirubin Transporter Family
• 2.A.66 The Multidrug/Oligosaccharidyl-lipid/Polysaccharide Flippase Superfamily
• 2.A.67 The Oligopeptide Transporter Family
• 2.A.68 The p-Aminobenzoyl-glutamate Transporter Family
• 2.A.69 The Auxin Efflux Carrier Family
• 2.A.70 The Malonate:Na⁺ Symporter Family
• 2.A.71 The Folate-Biopterin Transporter Family
• 2.A.72 The K⁺ Uptake Permease Family
• 2.A.73 The Short Chain Fatty Acid Uptake Family
• 2.A.74 The 4 TMS Multidrug Endosomal Transporter Family
• 2.A.75 The L-Lysine Exporter Family
• 2.A.76 The Resistance to Homoserine/Threonine Family
• 2.A.77 The Cadmium Resistance Family
• 2.A.78 The Branched Chain Amino Acid Exporter Family
• 2.A.79 The Threonine/Serine Exporter Family
• 2.A.80 The Tricarboxylate Transporter Family
• 2.A.81 The Aspartate:Alanine Exchanger Family
• 2.A.82 The Organic Solute Transporter Family
• 2.A.83 The Na⁺-dependent Bicarbonate Transporter Family
• 2.A.84 The Chloroplast Maltose Exporter Family
• 2.A.85 The Aromatic Acid Exporter Family
• 2.A.86 The Autoinducer-2 Exporter Family
• 2.A.87 The Prokaryotic Riboflavin Transporter Family
• 2.A.88 Vitamin Uptake Transporter Family
• 2.A.89 The Vacuolar Iron Transporter Family
• 2.A.90 Vitamin A Receptor/Transporter Family
• 2.A.91 Mitochondrial tRNA Import Complex
• 2.A.92 The Choline Transporter-like Family
• 2.A.94 The Phosphate Permease Family
• 2.A.95 The 6TMS Neutral Amino Acid Transporter Family
• 2.A.96 The Acetate Uptake Transporter Family
• 2.A.97 The Mitochondrial Inner Membrane K⁺/H⁺ and Ca²⁺/H⁺ Exchanger Family
• 2.A.98 The Putative Sulfate Exporter Family
• 2.A.99 The 6TMS Ni²⁺ uptake transporter Family
• 2.A.100 The Ferroportin Family
• 2.A.101 The Malonate Uptake Family
• 2.A.102 The 4-Toluene Sulfonate Uptake Permease Family
• 2.A.103 The Bacterial Murein Precursor Exporter Family
• 2.A.104 The L-Alanine Exporter Family
• 2.A.105 The Mitochondrial Pyruvate Carrier Family
• 2.A.106 The Ca²⁺:H⁺ Antiporter-2 Family
• 2.A.107 The MntP Mn²⁺ Exporter Family
• 2.A.108 The Iron/Lead Transporter Family
• 2.A.109 The Tellurium Ion Resistance Family
• 2.A.110 The Heme Transporter, heme-responsive gene protein Family
• 2.A.111 The Na⁺/H⁺ Antiporter-E Family
• 2.A.112 The KX Blood-group Antigen Family
• 2.A.113 The Nickel/cobalt Transporter Family
• 2.A.114 The Putative Peptide Transporter Carbon Starvation CstA Family
• 2.A.115 The Novobiocin Exporter Family
• 2.A.116 The Peptidoglycolipid Addressing Protein Family
• 2.A.117 The Chlorhexadine Exporter family
• 2.A.118 The Basic Amino Acid Antiporter Family
• 2.A.119 The Organo-Arsenical Exporter Family
• 2.A.120 The Putative Amino Acid Permease Family
• 2.A.121 The Sulfate Transporter Family
• 2.A.122 The LrgB/CidB holin-like auxiliary protein Family
• 2.A.123 The Sweet; PQ-loop; Saliva; MtN3 Family
• 2.A.124 The Lysine Exporter Family
• 2.A.125 The Eukaryotic Riboflavin Transporter Family
• 2.A.126 The Fatty Acid Exporter Family
• 2.A.127 Enterobacterial Cardiolipin Transporter Family

  2.B Nonribosomally synthesized porters

• 2.B.1 The Valinomycin Carrier Family
• 2.B.2 The Monensin Family
• 2.B.3 The Nigericin Family
• 2.B.4 The Macrotetrolide Antibiotic Family
• 2.B.5 The Macrocyclic Polyether Family
• 2.B.6 The Ionomycin Family
• 2.B.7 The Transmembrane α-helical Peptide Phospholipid Translocation Family
• 2.B.8 The Bafilomycin A1 Family
• 2.B.9 The Cell Penetrating Peptide Functional Family
• 2.B.10 The Synthetic CPP, Transportan Family
• 2.B.11 The Calcimycin or A23187 Carrier-type Ionophore Family
• 2.B.12 The Salinomycin Family
• 2.B.13 The Tetrapyrrolic Macrocyclic Anion Antiporter Family
• 2.B.14 The Lasalocid A or X-537A Ionophore Family
• 2.B.15 The Tris-thiourea Tripodal-based Chloride Carrier Family
• 2.B.16 The Halogen-bond-containing Compound Anion Carrier Family
• 2.B.17 The Isophthalaminde Derivative H⁺:Cl⁻ Co-transporter Family
• 2.B.18 The Pyridine-2,6-Dicarboxamine Derivative H+:Cl⁻ Co-transporter Family
• 2.B.19 The Calixpyrrole Derivative Family
• 2.B.20 The Prodigiosin Chloride/Bicarbonate Exchanger Family
• 2.B.21 The ortho-Phenylenediamine-bis-Urea Derivative Anion Transporter Family
• 2.B.22 The Imidazolium-functionalized Anion Transporter Family
• 2.B.23 The Homotetrameric Transmembrane Zn²⁺/Co²⁺:Proton Synthetic Antiporter, Rocker Family
• 2.B.24 The 2,6-Bispyridine Anion Carrier Family
• 2.B.25 The Peptide-mediated Lipid Flip-Flop Family
• 2.B.26 The Bis-functionalized Bis Conjugate Family
• 2.B.27 The Tris-Urea Anion Transporter Family
• 2.B.29 The Anionophoric Marine Alkaloid Tambjamine Family

  2.C Ion-gradient-driven energizers

• 2.C.1 The TonB-ExbB-ExbD/TolA-TolQ-TolR Family of Auxiliary Proteins for Energization of Outer Membrane Receptor -mediated Active Transport

  3. [Primary active transport]ers

3.A. P-P-bond hydrolysis-driven transporters

• 3.A.1 ABC transporters including BtuCD, molybdate uptake transporter, Cystic fibrosis transmembrane conductance regulator and others
• 3.A.2 The H⁺- or Na⁺-translocating F-type ATPase, V-type ATPase and A-type ATPase superfamily
• 3.A.3 The P-type ATPase Superfamily
• 3.A.4 The Arsenite-Antimonite efflux family
• 3.A.5 General secretory pathway translocon
• 3.A.6 The Type III Secretory Pathway Family
• 3.A.7 The Type IV Secretory Pathway Family
• 3.A.8 The Mitochondrial Protein Translocase Family
• 3.A.9 The Chloroplast Envelope Protein Translocase Family
• 3.A.10 H⁺, Na⁺-translocating Pyrophosphatase family
• 3.A.11 The Bacterial Competence-related DNA Transformation Transporter Family
• 3.A.12 The Septal DNA Translocator Family
• 3.A.13 The Filamentous Phage Exporter Family
• 3.A.14 The Fimbrilin/Protein Exporter Family
• 3.A.15 The Outer Membrane Protein Secreting Main Terminal Branch Family
• 3.A.16 The Endoplasmic Reticular Retrotranslocon Family
• 3.A.17 The Phage T7 Injectisome Family
• 3.A.18 The Nuclear mRNA Exporter Family
• 3.A.19 The TMS Recognition/Insertion Complex Family
• 3.A.20 The Peroxisomal Protein Importer Family
• 3.A.21 The C-terminal Tail-Anchored Membrane Protein Biogenesis/ Insertion Complex Family
• 3.A.22 The Transcription-coupled TREX/TAP Nuclear mRNA Export Complex Family
• 3.A.23 The Type VI Symbiosis/Virulence Secretory Pathway Family
• 3.A.24 Type VII or ESX Protein Secretion System Family
• 3.A.25 The Symbiont-specific ERAD-like Machinery Family
• 3.A.26 The Plasmodium Translocon of Exported proteins Family

  3.B Decarboxylation-driven transporters

• 3.B.1 The Na⁺-transporting Carboxylic Acid Decarboxylase Family

  3.C Methyltransfer-driven transporters

• 3.C.1 The Na⁺ Transporting Methyltetrahydromethanopterin:Coenzyme M Methyltransferase Family

  3.D. Oxidoreduction-driven transporters

• 3.D.1 family
• 3.D.2 The Proton-translocating Transhydrogenase Family
• 3.D.3 The Proton-translocating Quinol:Cytochrome c Reductase) Superfamily
• 3.D.4 Proton-translocating Cytochrome Oxidase Superfamily
• 3.D.5 The Na⁺-translocating NADH:Quinone Dehydrogenase Family
• 3.D.6 The Putative Ion -translocating NADH:Ferredoxin Oxidoreductase Family
• 3.D.7 The H₂:Heterodisulfide Oxidoreductase Family
• 3.D.8 The Na⁺- or H⁺-Pumping Formyl Methanofuran Dehydrogenase Family
• 3.D.9 The H⁺-translocating F420H2 Dehydrogenase Family
• 3.D.10 The Prokaryotic Succinate Dehydrogenase Family

  3.E. Light absorption-driven transporters

• Bacteriorhodopsin-like proteins including rhodopsin
• Bacterial photosynthetic reaction centres and photosystems I and II
• Light harvesting complexes from bacteria and chloroplasts

  4. Group translocators

4.A Phosphotransfer-driven group translocators

• 4.A.1 The PTS Glucose-Glucoside Family
• 4.A.2 The PTS Fructose-Mannitol Family
• 4.A.3 The PTS Lactose-N,N'-Diacetylchitobiose-β-glucoside Family
• 4.A.4 The PTS Glucitol Family
• 4.A.5 The PTS Galactitol Family
• 4.A.6 The PTS Mannose-Fructose-Sorbose Family
• 4.A.7 The PTS L-Ascorbate Family

  4.B Nicotinamide ribonucleoside uptake transporters

• 4.B.1 The Nicotinamide Ribonucleoside Uptake Permease Family

  4.C Acyl CoA ligase-coupled transporters

• 4.C.1 The Proposed Fatty Acid Transporter Family
• 4.C.2 The Carnitine O-Acyl Transferase Family
• 4.C.3 The Acyl-CoA Thioesterase Family

  4.D Polysaccharide Synthase/Exporters

• 4.D.1 The Putative Vectorial Glycosyl Polymerization Family
• 4.D.2 The Glycosyl Transferase 2 Family
• 4.D.3 The Glycan Glucosyl Transferase Family

  4.E. Vacuolar Polyphosphate Polymerase-catalyzed Group Translocators

• 4.E.1 The Vacuolar Polyphosphate Polymerase Family

  5. Transport electron carriers

5.A Transmembrane 2-electron transfer carriers

• 5.A.1 The Disulfide Bond Oxidoreductase D Family
• 5.A.2 The Disulfide Bond Oxidoreductase B Family
• 5.A.3 The Prokaryotic Molybdopterin-containing Oxidoreductase Family

  5.B Transmembrane 1-electron transfer carriers

• 5.B.1 The Phagocyte NADPH Oxidase Family
• 5.B.2 The Eukaryotic Cytochrome b561 Family
• 5.B.3 The Geobacter Nanowire Electron Transfer Family
• 5.B.4 The Plant Photosystem I Supercomplex Family
• 5.B.5 The Extracellular Metal Oxido-Reductase Family
• 5.B.6 The Transmembrane Epithelial Antigen Protein-3 Ferric Reductase Family
• 5.B.7 The YedZ Family
• 5.B.8 The Trans-Outer Membrane Electron Transfer Porin/Cytochrome Complex Family
• 5.B.9 The Porin-Cytochrome c Family

  8. Accessory factors involved in transport

8.A Auxiliary transport proteins

8.B Ribosomally synthesized protein/peptide toxins that target channels and carriers

8.C Non-ribosomally synthesized toxins that target channels and carriers

9. Incompletely characterized transport systems

9.A Recognized transporters of unknown biochemical mechanism

9.B Putative transport proteins

9.C Functionally characterized transporters lacking identified sequences