Thomas Murfyn was a native of Ely, Cambridgeshire, and son of George Murfyn. He was a member of the Worshipful Company of Skinners in the City of London, who served as Sheriff of London from 1511 to 1512, and as Lord Mayor of London from 1518 to 1519. Mark Noble claimed that Murfyn was probably not knighted until after his election to the mayoralty. Although Murfyn is often referred to in later documents as Sir Thomas Murfyn, there appears to be no record of his knighthood. It became common practice after Thomas Muryfn's mayoralty for Lord Mayors of London to be knighted and this may be one reason why later documents refer to him as "Sir". The misunderstanding may also be due to the translation of the form of address "Dominus" as "Sir". In his will, which was made on 2 September 1523 and proved in London on 15 October 1523, Murfyn refers to himself as "Thomas Mirfyn citizein and Alderman of the citie of London". The memorial to the graves lost in the Great Fire of London at St Paul's Cathedral, which lists "Sir Thomas Miryfn", may be perpetuating this error rather than evidence of a knighthood.
Family
Thomas married firstly, Alice Marshall, by whom he had thirteen children:
Thomas
John
George, who became a monk
Thomas
John
Frances
Richard
John
Robert
Edward, a wealthy London merchant who married Alice, widow of John Brigandine of Southampton, and daughter of Oliver Squier of Southby, Hampshire, by whom there were no surviving children. Alice subsequently married, circa 1528, Edward North.
Mary, who married, by 1523, another Lord Mayor of London, Sir Andrew Judde.
He married secondly, in 1519, Elizabeth, only daughter and heiress of Sir Angel Donne. alderman of London, and Anne Hawardine, of Cheshire. By Elizabeth, he had a daughter:
His last wife survived him and subsequently married, in 1524, Sir Thomas Denys by whom she had a son, Sir Robert Denys. Sir Robert married Mary, daughter of William Blount, 4th Baron Mountjoy, by whom he had a son, Thomas Denys. The arms of the Murfyns were, Or on a chevron sable a mullet argent; those of Donne, Azure semée of cross-crosslets or, a unicorn salient argent. Mirfyn is listed as one of the graves lost in the Great Fire of London in 1666, on a monument in the crypt of St Paul's Cathedral, together with several other Lord Mayors.