A series of strange disappearances have been occurring throughout Japan, and despite the police's efforts, no leads have been found apart from the fact that all of the victims were youths. Akatsuki Iride, a friendly and amicable teenage boy, is a popular uploader of "Let's Play" videos, one of his latest uploads consisting of an F2P game called "The Ones Within - Genome". Although online rumours claim that the game causes anyone who clears it to disappear, Akatsuki is wholly unaware until the rumours prove true -- he is summoned to a completely different world, and meets other teenagers like him: Karin Sarayashiki, Kaikoku Onigasaki, Himiko Inaba, Anya Kudou, Yuzu Roromori, Zakuro Oshigiri and Makino Aikawa. The eight teenagers are welcomed into what is known as the 13th Avenue, headed over by a strange man with an alpaca mask calling himself "Paca", and are informed of their task: to work together in clearing stages of the game and retrieving the "chromosome", a keycard-like token of completion, to subsequently reach 100 million viewers in this livestream where death and injury can all occur. Resistance is not tolerated; those who do are imprisoned in what is known as the "White Room" to wait alone for the rest in the Avenue to complete the game. Henceforth begins their trials in clearing this game, but what lies in wait for them is not only dangerous obstacles, with each member having a hidden past and dark secrets of their own.
An anime adaptation was announced via the manga's official Twitter account on May 23, 2018, later revealed to be a television series on September 13, 2018. The series is directed by Shin Ōnuma and animated by Silver Link, with Kento Shimoyama written the scripts, Mizuki Takahashi designed the characters, and Junichi Satou of Fhána composed the music at Lantis. It aired from July 7 to September 22, 2019 on AT-X, Tokyo MX, KBS, SUN, BS11, and TVA. Tasuku Hatanaka performed the series' opening theme song "not GAME", while Fhána performed the series' ending theme song "Boku wo Mitsukete". Funimation has licensed the series for a simuldub. The series ran for 12 episodes. An original video animation has been announced, and was bundled with the manga's 10th volume which was released on February 27, 2020.
