A beautiful, sophisticated New York woman who goes by the name Dunreath Henry seems to have it all. She is not only the private secretary to the wealthy and popular cartoonist Larry Larkin, she is also his fiancee. But back in Port Huron, Michigan when she was a girl, she was plain old Ethel Jankowski. And she used to be married to another cartoonist, the talented but neurotic Francis X. Dignan, who was once an associate of the famed Al Capp. One day, when Larkin's syndicate complains that his boy-and-dog comic strip "Snips and Runty" hasn't been as funny as it used to be, Dunreath hatches a scheme. Larry is leaving on a business trip and she is busy planning their honeymoon, so why not hire Dignan to ghost-write the strip? Dignan doesn't want to do it and certainly can't stand the snooty Larkin, but he needs the money for his psychiatrist, who is trying to find out why any setback or stress leads to Dignan experiencing a bad case of nausea. A lot of interesting developments take place in Larkin's Manhattan penthouse while the cartoonist is away. Dignan's strips are humorous and a hit. Old feelings begin to stir in Dunreath, having him around. Larkin's housekeeper, Gussie, begins to play matchmaker. A young orphan, Norman, arrives one day because Larkin intends to adopt him. Dignan is impressed until he discovers that Larkin's interested only in the publicity, not in the child. The TV programPerson to Person is coming to do a live interview, so Larkin wants a cute boy and happy puppy there by his side, just like his cartoon figures Snips and Runty. Dignan is offended. He is supposed to find a small dog for Larkin, but instead brings home one called Happy, a gigantic hound. Dignan also draws a cartoon using Larkin's name portraying Snips as a juvenile delinquent. And if that weren't enough, Larkin comes home to find Dignan and Dunreath dressed in matching pajamas, each having drunk one too many martini. Larkin fires Dignan just before the live TV appearance, which Dignan proceeds to interrupt by declaring his love for Larkin's fiancee. Dunreath decides to dump her betrothed and her fancy new name and live happily ever after with Dignan, Norman and Happy.