TOG superfamily
The transporter-opsin-G protein-coupled receptor superfamily is a protein superfamily of integral membrane proteins, usually of 7 or 8 transmembrane alpha-helical segments. It includes ion-translocating microbial rhodopsins and G protein-coupled receptors, Sweet sugar transporters, nicotinamide ribonucleoside uptake permeases, 4-toluene sulfonate uptake permeases, Ni2+–Co2+ transporters, organic solute transporters, phosphate:Na+ symporters and lysosomal cystine transporters.Families
Currently recognized families within the TOG Superfamily include:
A couple of the 3-D structures available for members of the following families include:
- SWEET family:
- MR family:, - high resolution structures
- PnuC family:
- GPCR family:
