Ricchetti led the Blue Cross and Blue Shield Association's political department from 1987 to 1989 and was executive director of the Democratic Senatorial Campaign Committee from 1990 to 1992. In the latter role, Ricchetti oversaw the upset victory of Democratic candidate Harris Wofford in the 1991 special election for Senate in Pennsylvania. From January 1993 to February 1996, he was a White House staffer in the Clinton administration, holding the title of Deputy Assistant to the President for Legislative Affairs. In this role, Ricchetti was President Clinton's principal liaison to the Senate. Ricchetti conducted work for the administration on the economic recovery act of 1993, the Telecommunications Act of 1996, and other legislation. From 1996 to 1998, Ricchetti was in the private sector, engaged in lobbying for clients at the governmental relations firm Public Strategies Washington. In September 1998, he returned to the White House, where he was tasked with handling relations with congressional Democrats amidst the impeachment proceedings against Clinton. In January 1999, Ricchetti became deputy White House chief of staff and gained a larger portfolio. In 2000, Ricchetti was appointed to President Clinton's task force on China PNTR during the president's last year. Along with Commerce Secretary William M. Daley, Ricchetti "led the Administration's successful campaign to secure permanent normal trade relations with China" and coordinated with leaders of major U.S. corporations, such as Boeing, American Online and Intel to "sell the benefits of the trade accord to Congress and the public.” In January 2001, Ricchetti founded and ran Ricchetti, Inc., a government relations and political consulting firm, with his brother Jeff Ricchetti. Over the following years, Ricchetti's firm represented a number of clients, including AT&T, Eli Lilly & Co., the American Hospital Association, United Technologies, the American Council of Life Insurers and the American Bankers Association. In March 2012 he was appointed to be counselor to Vice PresidentJoe Biden. Although Ricchetti had deregistered as a congressional lobbyist in late 2008 shortly after the election of Obama and Biden to the presidency and vice presidency, respectively. Ricchetti's appointment was controversial due to President Obama's promise to not appoint lobbyists and his issuance of "a tough new ethics policy meant to curb the revolving door between his administration and K street." Because Ricchetti had not lobbied personally for over two years, he did not require a waiver from the administration's policy. A statement from Biden's office in 2012 said that since 2008, Ricchetti had "advised clients on public policy, communications strategy, and grassroots efforts but did not act as a lobbyist with the federal government on behalf of any client." The Washington Post reported Ricchetti earned $1.8 million from his firm, Ricchetti Inc., the year before his appointment, and was owed another $217,000 from work he completed the same year as his appointment. In December 2013, Ricchetti succeeded Bruce Reed as chief of staff to the vice president, with the rank of Assistant to the President. Ricchetti was the chief planner for a possible Biden run in the 2016 presidential election. Richetti chaired Biden's presidential campaign in the 2020 elections, leading the campaign's efforts to raise funds from Wall Street financiers.