Spyridon

• Saint Spyridon, Orthodox saint
• Archbishop Spyridon of Athens, former Archbishop of Athens
• Spiro Agnew, 39th Vice President of the United States from 1969 to 1973, under President Richard Nixon
• Spyridon Belokas, Greek runner
• Spyros Christopoulos, Greek footballer
• Spyridon Gianniotis, freestyle swimmer
• Spyros Gogolos, Greek footballer
• Spyros Kokotos, Greek architect
• Spyros Kyprianou, 2nd President of the Republic of Cyprus
• Spyridon Lambros, Greek history professor and former Prime Minister of Greece
• Spiros Livathinos, Greek footballer and football coach
• Spyridon Louis, gold medalist of the first modern Olympic Marathon
• Spyridon Marinatos, 20th century archaeologist
• Spyros Markezinis, Greek politician
• Spyridon Merkouris, Greek politician, long-time mayor of Athens
• Spyros Moustakas, Greek writer
• Spyros Moustaklis, Greek democracy activist
• Spyros Paliouras, Greek writer
• Spyros Spyromilios, Greek Gendarmerie officer in the Greek struggle for Macedonia
• Spyridon Trikoupis, 2nd Prime Minister of Greece
• Spyridon Samaras, Greek composer
• Spyridon Stais, Greek politician
• Spyridon Trikoupis, former Prime Minister of Greece
• Spyros Vallas, Greek footballer
• Spyridon Vasdekis, Greek long jumper
• Spyridon Vassiliadis, Greek poet and playwright
• Spyros Vrettos, Greek poet
• Spyridon Xyndas, 19th century musician
• Martinus Spyridon Johannes Lodewijk, Dutch comics writer and cartoonist, and advertising adviser.