His first foray into comic illustration was with Singaporean tabloid paper The New Paper in 1995, contributing a comic strip titled Frankie and Poo. A compilation of the strips was published by Times Publishing in 1996. Shortly after his graduation from Rhode Island Liew got his first break into the American comics industry when Shelly Bond signed him on for Vertigo Comics' My Faith in Frankie together with Mike Carey and Marc Hempel. His work has appeared in the Flight Anthologies edited by Kazu Kibuishi, and he has served as editor of the Eisner-nominated Southeast Asian comics anthology Liquid City from Image Comics. In 2011, he was nominated for an Eisner award in the pencilling/inking category for his work on SLG and Disney's Wonderland, written by Tommy Kovac.Other titles include Marvel Comics' Sense and Sensibility adaptation, First Second Books' "The Shadow Hero" with Gene Luen Yang, An origin story for the obscure Golden-Age comic book hero The Green Turtle, who is thought to be the first Asian-American superhero and DC Comics' "Doctor Fate" with Paul Levitz. He is also the creator of Malinky Robot, a Xeric Award recipient in 2004 and winner of the “Prix de la Meilleure BD” at the Utopiales International SF Festival in Nantes in 2009. He was a recipient of Singapore's Young Artist Award in 2010.
''The Art of Charlie Chan Hock Chye''
The Art of Charlie Chan Hock Chye was first published and released by Epigram Books in 2015. It charts the life and career of a fictional comic book artist, the eponymous Charlie Chan Hock Chye, and by weaving together fact and fiction, and different genres, tells the story of the formative years of Singapore's modern history and the history of comics. Shortly before the book's release in Singapore, the National Arts Council withdrew its grant of $8,000 for the title, citing "sensitive content" and its potential to "undermine the authority and legitimacy" of the government. The comic became the best-selling local fiction title that year. The Art of Charlie Chan Hock Chye was published in the United States by Pantheon Books in 2016 and went on to make bestseller lists at Amazon and The New York Times, which is unprecedented for a Singaporean graphic novel. Besides winning the Singapore Literature Prize, it also won the Book of the Year accolade at the Singapore Book Awards in 2016. It was awarded the Pingprisen for Best International Comic in 2017. At the 2017 San Diego Comic-Con, Sonny Liew and The Art of Charlie Chan Hock Chye won three Eisner Awards -- Best Writer/Artist, Best U.S. Edition of International Material - Asia, and Best Publication Design. It was also nominated for three other Eisner Awards -- Best Letterer, Best Colorist, and Best Graphic Album - New.