After landing at Fort Michilimackinac in 1816, Juneau worked as a clerk in the fur trade before becoming an agent for the American Fur Company in Milwaukee. He had been summoned to the Milwaukee area by Jacques Vieau, a French-Canadian fur trader and the first permanent white settler in Milwaukee, Wisconsin. In 1818 Jacques Vieau hired Solomon Juneau, based on the accounting prowess Juneau had become known for, and Juneau's reputation for being able to deal well with the local native Americans. Juneau later married one of Vieau's daughters, Josette, and went on to found what was to become the City of Milwaukee. Juneau settled an area east of the Milwaukee River called Juneautown in 1818, which later joined with George H. Walker's Walker's Point and Byron Kilbourn's Kilbourntown to incorporate the City of Milwaukee. In 1831, Juneau began learning English and set in motion the naturalization and citizenship process. By 1835, he was selling plots of land in Juneautown. He built Milwaukee's first store and first inn, and was recognized for his leadership among newcomers to Milwaukee. In 1837 he started the Milwaukee Sentinel, which would become the oldest continuously operating business in Wisconsin. He was the first mayor of Milwaukee from 1846 until 1847, and was appointed its first Postmaster. Solomon Juneau High School, built in 1932, is named after him. The school is located at 6415 West Mount Vernon Avenue in Milwaukee. The hour bell in the clock tower of the Milwaukee City Hall, installed in 1896, is also named after him.
Personal
In 1820, Juneau married Josette, the Métis daughter of Jacques Vieau, a fur trader who had built a trading post overlooking the Menomonee Valley years before, and his Menominee wife. Josette was the oldest of 12 children, and was Menominee and French by ancestry. Through her alliances to the tribe, and the relationships fostered through Juneau's business in fur trading, it is reported that he was popular with the Menominee. After the treaty of 1848 between the United States and the Menominee, Juneau registered his wife and children as half-breeds of the Menominee Nation. In 1854, Juneau and family relocated to Dodge County, Wisconsin, where they founded the village of Theresa, named after Juneau's French-Canadian mother. Josette died there in 1855; Solomon died one year later in Keshena, Wisconsin, on a visit to the Menominee tribe. He died in the arms of Benjamin Hunkins, his "faithful friend and constant nurse." Six Menominee chiefs served as pallbearers at his funeral. He is buried at Calvary Cemetery, Milwaukee, Wisconsin. Juneau's grandson Paul O. Husting would be elected as a member of the United States Senate. The property that is believed to have once been the site of Juneau's residence is now the site of the Mitchell Building, listed on the National Register of Historic Places.