As an actor, he has played at many of the leading regional British theatres. He made his debut with the RSC at Stratford in 1983, and returned in 1986 to play Joey Percival in Shaw's Misalliance at the Barbican. Anthony Hopkins cast him as Willy Nilly in his production of Under Milk Wood for the official opening of the AIR Studios at Lyndhurst Hall, Hampstead in 1992, in aid of The Prince's Trust. Hopkins then asked Simon to personally assist him on his film and theatre productions of August, an adaptation of Anton Chekhov's Uncle Vanya, moved to North Wales. At the Orange Tree, Richmond, he starred as schizophrenic Victorian artist Louis Wain in Jane Coles' Cat with Green Violin. He played De Brie in the original 1992 UK production of David Hirson's multi award-winning La Bête and Bassanes in John Ford's The Broken Heart, both at the Lyric Hammersmith. In 1999, Treves lead the Singapore Repertory Theatre company production of M. Butterfly as Gallimard. In 2008, he played Richard Greatham in Hay Fever at Manchester Royal Exchange.
Television
On TV, Treves played Harold 'Stinker' Pinker in three series of Jeeves and Wooster, starring Hugh Laurie and Stephen Fry. His other TV appearances include Life, Black Earth Rising, Next of Kin, Stan Lee's Lucky Man, The Interceptor, EastEnders, Doctors, Red Dwarf X, Lynda La Plante's Above Suspicion: Silent Scream, Bodily Harm and , Soldier Soldier, The Lab, Boon and By the Sword Divided. As a child he appeared with his younger brother Patrick on the Christmas 1967 edition of Crackerjack.
Radio
Treves has acted in over one hundred radio productions for the BBC since his debut as Joseph Conrad's Lord Jim in 1985, and was a member of the Radio Drama Company from 1989 to 1991 and again in 2007–2008. Much of his work has been with award-winning radio producer Dirk Maggs, including Independence Day UK, The Amazing Spider-Man, The Adventures of Superman, The Gemini Apes and more recently, Boscobel and The Adventures of Sexton Blake. In the early 1980s, he regularly voiced trails for one of the first UK breakfast TV channels, TV-am. Other voice-over work was for Channel 4's Right to Reply, BBC One and numerous radio, film and commercial companies. He also voices a character on the computer game, .
Writing
His play Bitter with a Twist was produced by the Bristol Old Vic in 1999, and is published by Faber & Faber. It received its European premiere in Amsterdam in May 2011. Other commissions include two linked internet audio dramas – Ash and Gold, for totallyword.com; and an original short screenplay, Tweeny, commissioned by Brian Cox and Skreba Films. He recently adapted Jim Broadbent's A Sense of History for the stage; wrote and directed Smile for Miniaturists 24 at the Arcola; and devised and scripted Neither Here nor There, broadcast on BBC Radio 2 in August 2007.