Raised in Hamilton Township, Mercer County, New Jersey, Hampton attended Nottingham High School, where he was named New Jersey First Team All-Group IV, First Team All-South Jersey, and First Team All-Colonial Valley Conference honors after registering 17 tackles, 4 interceptions, averaging more than 38 yards per kickoff return, 13 yards per punt return on defense his senior season. He was named the Delaware Valley's Player of the Year by the 12th Man Touchdown Club Dinner. He was a key member of the school's Central JerseyGroup III championship as a junior. Rivals rated Hampton, a consensus three-star recruit, its 23rd-best prospect. He committed to Rutgers on National Signing Day in 2014 citing his desire to stay close to home.
College career
In 2018, Hampton tied for the Big Ten Conference lead in passes defended by safeties, including three interceptions, two of which came in week 9 against Wisconsin. Combined with his ten tackles that game, he was named Reese's Senior Bowl Defensive Player of the Week. Senior Bowl Executive Director Jim Nagy pointed out:
"The first thing that will catch scouts’ attention is that Hampton has a background at cornerback, which is important in the sense that he has more experience in man coverage, even if it’s just at the high school level, than most safety prospects. The attribute that showed up most in the game against the Badgers was his ball skills. During our tape study, we liked him the most when the ball was in the air. On both his two picks last Saturday, one when he drove on an out route and another where he undercut a corner route, Hampton looked really natural playing the ball. The other aspect of Hampton’s game that stood out last week was his deep field instincts. Scouts determine where to project safeties, either free or strong, based on where they look most natural playing and Hampton looks most comfortable in the middle of the field. Some guys have a feel for routes and Hampton consistently put himself in the position to make plays."
In the lead-up to the 2019 NFL Draft, Hampton accepted an invitation to the East-West Shrine Game. He was also invited to participate in the 2019 NFL Draft Combine. Following the week of the Shrine Game, Bleacher Report's Matt Miller included Hampton among the "2019 NFL Draft's Biggest Winners from NFLPA Bowl, Shrine Game Weeks," noting, "He's a hitter with a fierce mentality and has the athleticism and size to become an NFL contributor." Hampton was drafted by the New Orleans Saints in the sixth round of the 2019 NFL Draft. He played in five games before being placed on injured reserve on December 17, 2019.