Seifert was first discovered by a talent scout/make-up artist at the age of 14. After only a few castings, Seifert received a call to join her first fashion show for a French eyewear company. In 1998 she joined the Philippines' Elite Model Search where she won the Viva Look of the Year title and represented the Philippines in the international Elite Model Look Search, which was held in Nice, France. Seifert was part of the Colgate Mintirinsead campaign "Minti Cool" along with Anne Curtis and Aubrey Vizcarra. When Colgate decided to have a remake of that ad campaign a few years later, Michael Seifert appeared as the male lead role alongside the new cast. She was a muse for two Philippine Basketball Association teams, a professional basketball league in the Philippines: Red Bull in 2002 and FedEx in 2003. An avid basketball player herself, she also played for her school's women's team. Seifert has done several national and international advertising commercials and graced many of Manila's hottest fashion shows including Philippine Fashion Week, Speedo, Benetton, Lancôme, and Bulgari Jewelry. While seen in ample fashion shoots, Seifert has written articles for magazines, well- tackling social awareness issues. In addition, she has been visible in numerous print ads and appeared on magazine covers including MEGA, Speed, and A&F. However, it was through her hosting job in the late night show "Master Showman," that she gained much recognition and popularity all over the Philippines. Aside from Master Showman, she also hosted the now defunct television show Campus Video with co-host Derek Ramsey. Her hosting opportunities were soon followed by traveling in and out of the Philippines as she signed up with a Thailand-based modeling agency.
Seifert, a vegetarian, crowned Miss Philippines Earth 2009, the 9th edition of the "beauty for a cause" pageant. She bested 49 other contestants representing various Filipino communities in the beauty contest that promotes environmental awareness. The event was broadcast by ABS-CBN in the Philippines and by The Filipino Channel internationally. She was crowned by the outgoing titleholder, Miss Earth 2008Karla Henry, on 10 May 2009 at The Arena Entertainment and Recreational Center of the People, San Juan City. Seifert was also an early favorite in the Miss Philippines Earth 2009 pageant, collecting four special citations: Best in Cultural Costume, Miss RCBC E-Woman, Gandang Ricky Reyes and Best in Swimsuit. Seifert’s white "Pearl of the Orient" gown, a modern interpretation of the terno featuring a feathered mask and layered Spanish lace embellished in crystals, beads, and pearls was designed by Frederick Peralta. She won P250,000, plus other prizes, and represented the Philippines in the Miss Earth pageant later that year. She also impressed the judges during the final question and answer portion of the pageant with her answer to the final question “With global environment changing, what would you like to change in yourself that will make you a better pro-environment person?" Seifert said: “When I joined Miss Earth I became aware of the things I can do as a Filipino and as a citizen of the world. I would like to share this awareness with more people, whether on a personal level or through the media. I want to make a difference in every little way I can.” Negros Occidental Governor Isidro Zayco said Negrenses welcomed her success in the pageant. On 25 May 2006, she paid a courtesy call on Governor Zayco at the Provincial Capitol and met with mayors and board members of Negros Occidental province.
