Appleton was born in New Ipswich, New Hampshire. His family had come there from Ipswich, Massachusetts where relatives lived into the present. From 1790 to 1792, he cleared fields in Maine for farming. He also taught school. For a time he kept a store in Ipswich. In 1794, he moved to Boston where he became an importer in partnership with his brother Nathan as S. & N. Appleton, buying European dry goods at auction and for resale to country traders in exchange for homespun cloth as well as pot and pearl ash for export to Britain. He also later established cotton mills at Waltham and Lowell, Massachusetts. After 1799 he passed much of his time in Britain, and at age 53 married a widow, Mrs. Mary Gore, with whom he had no children. He retired from business in 1823. After retirement he devoted much of his fortune to charity, including his gift funding the Appleton Cabinet at Amherst College, built to house the Hitchcock Ichnological Cabinet, and the Appleton Chapel at Harvard University. He endowed the academy at New Ipswich with a fund which secured its permanence, and founded the professorship of natural philosophy of Dartmouth College, with a gift of $10,000. Appleton served as a vestryman of King's Chapel from 1830 to 1840, and a monument to him sits on the north wall of the chapel. Wilson's biographical directory of Boston's business aristocracy, published 1848, noted that it was “to the credit of Samuel Appleton, that he commenced life with a single four-pence half penny, paid to him by a drover who passed his father's house, for assistance in driving .” At his death, Appleton's fortune amounted to nearly $1,000,000, and he had given away nearly as much as that during his lifetime. By his will he placed property to the amount of $200,000 in the hands of his executors, “to be by them applied, disposed of, and distributed, for scientific, literary, religious, and charitable purposes.” The Samuel Appleton Building located on 110-114 Milk Street, Boston is currently under study as a Boston Landmark by the Boston Landmarks Commission.
Historic ship
The 1846 ship Samuel Appleton, 808 tons, was built by P. Curtis in Medford, MA, and owned by the prominent merchant Daniel Pinckney Parker of Boston.