Salios made his debut in an event for previously unraced juveniles over 1600 metres at Tokyo Racecourse on 2 June and won from Absolutismo and six others. After a break of four months the colt returned to the track and was stepped up in class to contest the Grade 3Saudi ArabiaRoyal Cup at Tokyo on 5 October when he was ridden by Shu Ishibashi and started the 0.5/1 favourite against eight opponents. He raced in third place before moving up to dispute the lead in the straight and got the better of the filly Cravache d'Or to win by one and a quarter length in a race record time of 1:32.7 for 1600 metres. On 15 December Salios was partnered by Ryan Moore when he started favourite for the Grade 1 Asahi Hai Futurity Stakes at Hanshin Racecourse. His fifteen opponents included Taisei Vision, Red Bel Jour, Bien Fait and Meiner Grit. After racing in third place behind Bien Fait and Meisho Titan he went to the front early in the straight and steadily increased his lead to win by two and a half lengths from Taisei Vision. His winning time of 1:33.0 was a new record for the race, beating the mark of 1:33.3 set by Danon Premium in 2017. Ryan Moore commented "He was a lovely horse... he was still very green on the turn so he should run even faster in the future. He’s a big powerful colt and when I sat on him you get the impression that he’s very strong already, but he should improve and be even better as he gets older being the size that he is and hopefully he’ll carry on". In January 2020, at the JRA Awards for 2019, Salios finished runner-up in the poll for Best Two-Year-Old Colt, losing to Contrail by 77 votes to 197. In the official Japanese rankings however, Salios was rated the best two-year-old of 2019, one pound ahead of Contrail.
2020: three-year-old season
On his first run of 2020 Salios faced Contrail in a "much-anticipated showdown" for the Satsuki Sho over 1200 at Nakayama Racecourse and went off the 2.8/1 third choice in the betting. Ridden by the Australian jockey Damian Lane he raced up the inside before taking the lead in the straight but came of second best in a sustained struggle with Contrail, beaten half a length. Noriyuki Hori later said, "It was a difficult race last time, and he didn't change leads in the homestraight, as well as not getting the best ground, making things tough for him". Lane was again in the saddle when Salios was moved up in distance and started 3.4/1 second favourite behind Contrail for the Tokyo Yushun over 2400 metres at Tokyo. After being restrained in mid-division he was forced to race on the wide outside to obtain racing room and finished strongly but was never able to get on terms with Contrail and finished second, beaten three lengths by the winner.