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SIB-1893
SIB-1893
is a
drug
used in
scientific research
which was one of the first
compounds
developed that
acts
as a
selective
antagonist
for the
metabotropic glutamate receptor
subtype
mGluR
5
. It has
anticonvulsant
and
neuroprotective
effects
, and
reduces
glutamate
release
. It has also been found to
act
as a
positive allosteric modulator
of mGluR
4
.