SAP130


Histone deacetylase complex subunit SAP130 is an enzyme that in humans is encoded by the SAP130 gene.

Function

SAP130 is a subunit of the histone deacetylase -dependent SIN3A corepressor complex.

Interactions

SAP130 has been shown to interact with:
s have been used in the study of SAP130 function. A conditional knockout mouse line called Sap130tm1aMbp was generated at the Wellcome Trust Sanger Institute. Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Additional screens performed: - In-depth immunological phenotyping