Reed was born in St Pancras, London. His father had been Second Head Waiter at the London Trocadero Restaurant before the First World War but was killed by a stray shell shortly after his arrival in France in 1917 when his son was less than a year old. Reed grew up with his mother Theresa at 9 Leigh Street in the Kings Cross area of London, and was a choirboy at St Pancras Church, close to St Pancras Station. Early on he was interested in radio, and built himself an early form of citizen's band radio. He attended Thanet Street Junior School in St Pancras, and from there gained a scholarship to the Regent Street Polytechnic, where he qualified as an electronic engineer. At around that time he also built himself an early form of TV, called a Baird Televisor. In 1938, he was taken on as a peripatetic engineer for the BBC, and helped on many outside broadcasts.
In 1940, Ronnie Reed was requested by the BBC to go on an assignment. This turned out to be a visit to Wormwood Scrubs prison, which is where MI5 had its headquarters at the beginning of the Second World War. He was taken to a cell in which there was a German spy who had just landed. This was Agent Summer, a Swedish citizen whose real name was Gösta Caroli. His interrogators wanted Reed to help supervise this agent's first broadcast back to Germany, in which he would tell them he had landed safely. Reed then supervised other double agents, such as Agent Tate, during the rest of the War. He was permanently seconded to MI5, which deals with countering subversion. He was Case Officer for a number of agents, of whom the most important was Agent Zigzag, whom he supervised from December 1942 until August 1944. Another of Ronnie Reed’s involvements dates from the time when the stratagem of "The Man Who Never Was" was being prepared in 1943. Commander Ewen Montagu, who thought up the scheme, needed to produce an identity card for the corpse on which fake invasion plans were to be planted. For the card, he needed a photograph, but he could find no-one who resembled the body. Then, at a meeting to discuss double-agents, he found himself seated opposite Ronnie Reed and realised that "he could have been the twin brother of the corpse". Reed’s photograph was therefore used for the Identity Card.
During World War II, Ronnie Reed had met Mary Dyer through the Common Wealth Party – a radical alternative political party, at a time when all the main parties had joined the Coalition Government. They married in June 1946, and had two sons, Nicholas in 1947 and Adrian in 1949. By the early 1950s Reed was a senior officer in MI5, and indeed was the officer to whom William Skardon, Scotland Yard's top interrogator, reported, when Skardon was questioning, and extracting a confession from, the atomic spyKlaus Fuchs. By then, Reed was in charge of the section which dealt with Russian spies, and thus was intimately involved in the investigation of those who spied for Russia, in particular, Kim Philby, Guy Burgess and Donald Maclean. Reed, like all his fellow officers, had been completely hoodwinked by Philby, and as a result he might have been demoted or moved. However, he did spot that Jenifer Hart, wife of Professor H. L. A. Hart, might in fact be spying for Russia. In 1957, Ronnie Reed was seconded to the Foreign Office when he, and his wife and sons, went to New Zealand for a three-year posting. Officially First Secretary at the British High Commission, he was actually helping a New Zealander, Bill Gilbert, to set up a New Zealand MI5, rather than such investigations being run from England in the colonial fashion. In 1960 they returned to the UK and bought a house at 2 Court Lane Gardens, Dulwich, South London. Reed retired in 1976, at the age of 60, and died in 1995 in Dulwich. Reed contributed a monograph on radio work during World War II; it was published as an appendix to the Official history of British Intelligence during the War.