Gosden was a lecturer in physiology at the University of Edinburgh Medical School from 1976 to 1994, a professor of reproductive sciences at Leeds School of Medicine from 1994 to 1999, and scientific director of reproductive biology at McGill University Health Centre from 1999 to 2001. His departure from the UK was the hook for an article in The Independent about a wave of scientists emigrating from the UK due to negative public opinion about scientists in the UK. In 2001, Gosden became the director of scientific research at the Jones Institute for Reproductive Medicine at Eastern Virginia Medical School, where he was named the Howard & Georgeanna Professor of Reproductive Medicine. He left the Jones Institute in 2004 to become research director of reproductive biology at Weill Cornell Medicine, where his wife was on the faculty; part of the reason why Gosden left the institute was negative public opinion and criticism due to its creation in 2001 of an embryonic stem cell line, as was noted in a report in the journal, Science. He retired from research in 2010. Gosden's research was focused on understanding, forecasting and treating infertility. His work focused on understanding basic biology around development and senescence of ovarian follicles and ovaries in women, including trying to mathematically model those processes, and he did important translational research on ovarian tissue cryopreservation and on ovary transplantation; his interests also extended to uterus transplantation. In 1994, Gosden and colleagues announced that they had successfully restored fertility to and achieved two live births in sheep through ovarian tissue autotransplantation, one of which had been frozen then thawed. In collaboration with Sherman Silber, this technique was later extended to women using tissue or the entire ovary transplanted from an identical twin. , there had been 86 live-births and were 9 on-going pregnancies directly as a result of these types of ovarian tissue transplantation. Gosden was a scientific advisor to Celmatix, Inc., which was founded by his former student. He spoke out against the controversial claims made by OvaScience, a company founded in 2012, that it could help older women conceive using putative oogonial stem cells.
Personal life
Gosden married Carole Ann Walsh in 1971 and they had two sons before their divorce in 2003. In 2004 he married Lucinda Veeck, whom he had met at the Jones Institute in Norfolk when she was working there. In the same year he moved to New York to work at Weill Cornell Medicine, where Veeck was director of clinical embryology. In 2010, they both moved to Williamsburg, Virginia, where they run an independent publishing company, Jamestowne Bookworks, which Gosden opened as outlet for his own works, to allow him to control his own works after a life of assigning copyright to biomedical publishers, and to publish other people's work that interested him.
