The relationship between mathematics and physics has been a subject of study of philosophers, mathematicians and physicists since Antiquity, and more recently also by historians and educators. Generally considered a relationship of great intimacy, mathematics has been described as "an essential tool for physics" and physics has been described as "a rich source of inspiration and insight in mathematics". In his work Physics, one of the topics treated by Aristotle is about how the study carried out by mathematicians differs from that carried out by physicists. Considerations about mathematics being the language of nature can be found in the ideas of the Pythagoreans: the convictions that "Numbers rule the world" and "All is number", and two millennia later were also expressed by Galileo Galilei: "The book of nature is written in the language of mathematics". Before giving a mathematical proof for the formula for the volume of a sphere, Archimedes used physical reasoning to discover the solution. From the seventeenth century, many of the most important advances in mathematics appeared motivated by the study of physics, and this continued in the following centuries. The creation and development of calculus were strongly linked to the needs of physics: There was a need for a new mathematical language to deal with the new dynamics that had arisen from the work of scholars such as Galileo Galilei and Isaac Newton. During this period there was little distinction between physics and mathematics; as an example, Newton regarded geometry as a branch of mechanics. As time progressed, increasingly sophisticated mathematics started to be used in physics. The current situation is that the mathematical knowledge used in physics is becoming increasingly sophisticated, as in the case of superstring theory.
Explain the effectiveness of mathematics in the study of the physical world: "At this point an enigma presents itself which in all ages has agitated inquiring minds. How can it be that mathematics, being after all a product of human thought which is independent of experience, is so admirably appropriate to the objects of reality?" —Albert Einstein, in Geometry and Experience.
Clearly delineate mathematics and physics: For some results or discoveries, it is difficult to say to which area they belong: to the mathematics or to physics.
What is the geometry of physical space?
What is the origin of the axioms of mathematics?
How does the already existing mathematics influence in the creation and development of physical theories?
Is arithmetic analytic or synthetic?
What is essentially different between doing a physical experiment to see the result and making a mathematical calculation to see the result?