Anthony accepted an athletic scholarship to attend the University of Florida in Gainesville, Florida, where he was a wide receiver and a key target in head coach Steve Spurrier's Florida Gators football team from 1994 to 1996. Anthony showed his stuff as a freshman in Spurrier's "fun 'n' gun" offense in 1994, when he caught an 87-yard touchdown pass from Gators quarterbackEric Kresser against the Southern Mississippi Golden Eagles. As a junior in 1996, he played an instrumental role in the Gators' 12–1 national championship season, catching seventy-two passes to lead the Southeastern Conference with 1,293 yards, and setting the SEC regular season record with eighteen touchdown catches. Both Anthony and his fellow Gator wideout, Ike Hilliard, were first-team All-SEC selections and earned consensus first-team All-American honors. During his three college seasons, the Gators won three consecutive SEC Championship Games in 1994, 1995, and 1996. In the aftermath of his All-American junior season and the Gators' Bowl Alliance national championship victory over the Florida State Seminoles in the Sugar Bowl, Anthony decided to forgo his final season of NCAA eligibility and enter the NFL Draft. He finished his college career with 126 receptions for 2,274 yards and twenty-six touchdowns. His eighteen receiving touchdowns in 1996 remains the SEC and Gators' team record. In a 2006 series written for The Gainesville Sun, Anthony was recognized as No. 17 among the 100 all-time greatest Gators of the first 100 years of Florida football. He was inducted into the University of Florida Athletic Hall of Fame as a "Gator Great" in 2009.
Professional career
His home state Tampa Bay Buccaneers chose Anthony in the first round of the 1997 NFL Draft, and he played for the Buccaneers for five seasons from to. In, Anthony recorded thirty-five receptions for 448 yards and four touchdowns. In his fourth game, Anthony became the second youngest NFL player ever to record a touchdown reception. In, he set career highs with fifty-one receptions for 708 yards and seven touchdowns. In perhaps his finest game as a Buccaneer, Anthony recorded 126 receiving yards with two touchdowns against the Jacksonville Jaguars on November 15, 1998. During the year, he also finished eighth in the NFL in all-purpose yards, totaling 1,869 yards. In, Anthony had thirty receptions for 296 yards, and scored one touchdown. In, Anthony had fifteen receptions for 232 yards and four touchdowns. In his final NFL season in, he recorded thirteen receptions for 162 yards. Anthony finished his five-year NFL career with 144 receptions for 1,846 yards and sixteen touchdowns.