His full name was Publius Calvisius Sabinus Pomponius Secundus, as indicated by two fragmentary inscriptions from Germania Superior. For some time, Pomponius' praenomen was uncertain; Publius was not a regular name of the Pompilii, and Olli Salomies discusses the possibility that it might have been Gaius, but notes that a Publius Calvisius Sabinus was attested as existing in Spoletium, and concludes that it is "possible to assume with some confidence" that he had been adopted by a Publius Calvisius Sabinus. That his praenomen was Publius, at least after his adoption, seems to be confirmed by an inscription from Veii, dating from his consulship, another from Cyrenae, when he was proconsul, and one from Mogontiacum, when he was Legatus Augusti pro praetore.
Pomponius was one of the friends of Sejanus, who was consul in 31, and on the latter's fall in October of that year, Pomponius was placed under house arrest, where he remained until Caligula released him. During either the reign of Caligula or Claudius he was governor of the public province of Creta et Cyrenaica. It was during the reign of Claudius that Pomponius acceded to the consulship. He was afterwards governor of Germania Superior from the year 50 to 54; during his office Pomponius conducted a successful campaign, described by Tacitus, against the German Chatti, where, after forty years, survivors of the Battle of the Teutoburg Forest were freed from slavery. For this he received ornamenta triumphalia.
Writings
It was by his tragedies that Secundus obtained the most celebrity. They are spoken of in the highest terms by Tacitus, Quintilian, and the younger Pliny, and were read even in a much later age, as one of them is quoted by the grammarian Charisius. These tragedies were first put on the stage in the time of Claudius. Quintilian asserts that he was far superior to any writer of tragedies he had known, and Tacitus expresses a high opinion of his literary abilities. Secundus devoted much attention to the niceties of grammar and style, on which he was recognized as an authority. His subject matter was Greek, with one known exception, a praetexta called Aeneas. Tragedians in the Julio-Claudian and Flavian periods typically were men of relatively high social status, and their works often expressed their political views under an insufficient veil of fiction. Only a few lines of his work remain, some of which belong to Aeneas.