Prostaglandin E synthase
Prostaglandin E synthase is an enzyme involved in eicosanoid and glutathione metabolism, a member of MAPEG family. It generates prostaglandin E from prostaglandin H2.
The synthase generating PGE2 is a membrane-associated protein.
Isozymes
Humans express three prostaglandin-E synthase isozymes, each encoded by a separate gene:
