Prebediolone acetate


Prebediolone acetate, also known as 21-hydroxypregnenolone 21-acetate or 21-acetoxypregnenolone, as well as 3β,21-dihydroxypregn-5-en-20-one 21-acetate, is a synthetic pregnane steroid which is described as a glucocorticoid and has been used in the treatment of rheumatoid arthritis. It is the C21 acetate ester of prebediolone, the C21 hydroxylated derivative of pregnenolone. Prebediolone acetate has been known since at least 1950. The compound is also an intermediate in a synthesis of deoxycorticosterone acetate.