He worked first in a place called Mergui. In 1749 he apposed the erection of a stone in front of his Church. The stone is claimed to have contained abusive language towards Catholicism and for that reason it was called scandal stone. After two months of fighting, the Governor relented. From 1742 to 1750, he worked as the provicar of the Tenasserim. He came back to Bangkok on 22 January 1755 and was appointed titula bishop of Thabraca and Coadjutor of Siam. Since his predecessor Jean de Lolière-Puycontat died before consecrating him, Brigot went to Manila to receive his episcopal consecration on 24 August 1757 from Bishop Juan de La Fuente Yepes. Dunring the Burmese–Siamese War of 1767 Bishop Brigot, his missionaries together with their Christians and seminarians, a Jesuit, Dominicans, another Portuguese priest, and their Christians were taken prisoners. Seeing fellow Christians in misery, he gave them everything he had, he even sold his episcopal ring. During the month of May they were taken to Tavoy and then in November to Rangoon. The Franciscans and Barnabites missionaries in this city, chose him as arbitrator on an issue that divided them, and accepted his decision. On 31 January 1768 he consecrated Giovanni Maria Percoto as the Titular Bishop of Maxula Prates and the Vicar Apostolic of Ava e Pegù. He left in March of that year to Pondicherry.
In Karnatic Mission
After the Suppression of the Society of Jesus, the Karnatic Mission was given to the Paris Foreign Missions Society. He was appointed as its Superior by Pope Pius VI on 30 September 1776. He devoted himself to the reunion of the Jesuits and MEP missionaries and encouraged them to work together. By a decree issued on 7 September 1778 he gained 13 jurisdictions, which gave him authority over all Christians in the territory of the French colony excluding Europeans and Creoles who remained subject to the Capuchins. Later his jurisdiction was extended over the Madurai and the Mysore. He consulted with Rome on some Indian customs and caste, and wisely applied the guidelines he received.
Death
In 1785, he chose Nicolas Champenois as coadjutor and consecrated him as the Titular Bishop of Doliche on 5 November 1786. Because of old age and sickness, he entrusted the administration to his coadjutor. He died in Pondicherry on 8 November 1791.
