Philippe was educated by the clegy of Cavaillon and was made Canon of the cathedral chapter of Cavaillon on 22 March 1328. He next was promoted to archdeacon on 26 August 1330. He then took a position as provost on 18 September 1331. Philippe was promoted to the episcopate when he was a deacon in 1333 by Pope John XXII.
Philippe formed a long lasting friendship with Petrarch from 1337 until his death in 1372. Philippe had a villa not far from Avignon in the village of Vaucluse high on a cliff with a view. Petrarch built a home in Vaucluse after visiting his friend Philippe, who had built his castle on the site of a 7th-century BC Oppidum. From Philippe's castle the view was beautiful and is no wonder the bishop selected this lofty spot. Living just a short twenty-minute walk from one another, they developed a very close relationship that lasted a lifetime. Petrarch dedicated a book to his friend, who "treated him as a brother", despite his later status as Cardinal. Among the intimates of Petrarch's old age there seems to be only one name missing in Petrarch's will, which is Philippe's. Their friendship had begun in 1337 when Petrarch moved to Vaucluse. They stayed close friends up until Philippe's death in 1372. The fact that in spite of this undoubtedly very close relationship Petrarch did not include his friend Philippe in his Last Will and Testament is explained by the assumption that Petrarch could not think of any bequest suitable to a man of such high status as that of a prince. Petrarch made a collection of 350 letters he personally wrote called Epistolae familiares. In among these letters in 1346 Petrarch writes what is called De vita solitaria, a treatise composed of two books and dedicated to Philippe de Cabassoles. In Book XXII of Familiar Letters is Petrarch's books of these letters to Philippe which he delivered 20 years after he wrote them. Also in addition to these books of letters he wrote some very special letters that he held out of the set of Epistolae familiares, which was later put into a set of 19 letters called Liber sine nomine. Letters 1 and 12 are letters Petrarch wrote to his friend Phillippe that are in this reserved set of letters "without a name" of the recipient. Petrarch dedicated his work De vita solitaria to his friend Philip. A dedication to him is in the preface. Historian Wilkens tells of part of a letter Petrarch sent to Philip in 1371 that shows their friendship,
Death and after
Pope Gregory XI sent Philippe to Perugia and designated him papal legate and governor of Umbria in early 1372. Before his term ended he died on 27 August 1372 and was buried in the Carthusian monastery of Bonpas, near Avignon. Later his body was transferred to the church of Caumont-sur-Durance in 1833. In October 1926, a commemorative plaque was placed de l'Evêché at Cavaillon in the ruins of his palace.