In 1993 Klimkin started his career at the Ukrainian Foreign Ministry, where he would hold a variety of positions. Early on he served as an attaché and second secretary in the department of military control and disarmament, also working in the departments involved with German diplomacy, nuclear and energy security, and economics. By 1997 he was working directly for the futureVice Prime MinisterKostyantyn Gryshchenko, who would later appoint Klimkin as his deputy minister. Klimkin was appointed Minister-Counselor of the Ukrainian Embassy in the United Kingdom in 2004, a position he held until 2008. In March 2008 he was named the Ukrainian Foreign Ministry's director for their European Union department. On 21 April 2010 he became Deputy Foreign Minister in the First Azarov Government of Ukraine. As deputy Klimkin played a central role in negotiating the Ukraine–European Union Association Agreement, particularly in its early stages in 2012. According to Gazeta.ru, during those years Klimkin was "the face of European integration of Ukraine," as he led a delegation of negotiators with the EU. According to Ukrayinska Pravda, the rejection of European integration with Ukraine in November 2013 was "a personal disappointment to Klimkin, who dedicated many months of his life to issue."
Ambassador to Germany
He served as both Deputy Foreign Minister and Chief of Staff of the Ukrainian Foreign Ministry until 22 June 2012, when he was appointed Ambassador of Ukraine to Germany. As ambassador he has been influential in a number of international negotiations; in early June 2014, that included talks to stop the fighting in eastern Ukraine, when he met with Heidi Tagliavini of the Organization for Security and Co-operation in Europe and the Russian Ambassador to Ukraine, Mikhail Zurabov. According to AFP news agency, "The talks have since produced a peace initiative that includes Poroshenko's ceasefire proposal and the introduction of a new constitution that gives broader rights to Ukraine's regions - a key Moscow demand."
;Appointment In early June 2014, Klimkin's candidacy for the Minister of Foreign Affairs of Ukraine was proposed by Petro Poroshenko, the recently appointed Ukrainian President. On 19 June 2014, 335 MPs of the Verkhovna Rada voted for his appointment. This made his approval unanimous, excluding the 35-member faction "Freedom," which didn't vote entirely. Klimkin was sworn in that day. His appointment was met with voiced approval by academics such as Hryhoriy Nemyria, and that day Klimkin was congratulated by phone by foreign ministers such as Laurent Fabius of France, John Baird of Canada, and Frank-Walter Steinmeier of Germany. He also met with the OSCE chairman, Heidi Tagliavini. Russia's Deputy Foreign Minister, Grigory Karasin, stated on 19 June that "we wish the new minister success and are ready for contact with him," also stating that Klimkin is known in their department as a "skilled diplomat." The following day, Klimkin and the Russian Foreign Minister, Sergei Lavrov, discussed "measures to resolve Ukraine's crisis" on the phone, focusing on Poroshenko's peace plan and controlling the Ukrainian border. ;Policies as minister According to the AFP news agency, Klimkin's appointment "is seen as a step toward better relations with Russia." Also, according to NBC, Klimkin is "Committed to European integration he has played a key role in negotiating the association and free trade agreements with the European Union, which Ukraine is expected to sign later ." On 29 Augustus 2019 Vadym Prystaiko replaced Klimkin as Foreign Minister of Ukraine.
Personal life
Klimkin was married to a fellow diplomat, Natalia, and has two sons. Natalia Klimkin holds the post of first secretary of the Embassy of Ukraine in the Netherlands and is responsible for policy issues and culture. His second wife is Maryna Mykhaylenko, the daughter of a Russian Major General Yury Mykhaylenko.