Park End Street was built in 1769–70 as part of New Road, a new turnpike road between central Oxford and the west. It bypassed the earlier and narrower Hythe Bridge Street to the north and St. Thomas's High Street to the south. Pacey's Bridge was built to carry the eastern part of Park End Street across Castle Mill Stream, which is part of the River Thames. The street's name is derived from a wharf where coal from Parkend in the Forest of Dean was delivered by barge. From the 1840s, railways took an increasing share of coal traffic. Inland waterways' share of the traffic declined and in 1885 Park End Wharf was redeveloped for other purposes.
Public house
By the early part of the 19th century, a public house had been opened at 1 Park End Street on the north side of the street just east of the bridge. It was named the Queen's Arms, almost certainly after Charlotte of Mecklenburg-Strelitz, Queen Consort of George III. The pub is currently called Lighthouse after being refurbished in 2014.
Breweries
In 1885 Park End Wharf was redeveloped as the site of the Tower Brewery, which its owner F. Phillips then expanded in the 1890s and 1900s to designs by local architect H.J. Tollit. Before the Tower Brewery was built, the Eagle Brewery was already on a site next to the wharf. Its owner William Miller renamed it the Eagle Steam Brewery to advertise its conversion to steam powered brewing, and then in 1869 sold it to J.N. Weaving. In 1871 Weaving demolished part of the brewery to build a granary and in 1872 he added a three-storey malthouse. Weaving's successor F. Phillips continued to expand the business, including the addition of a new tower brewhouse, chimney and other buildings in 1885 designed by H.J. Tollit. No buildings of either the Eagle or the Tower breweries now survive.
Archer, Cowley & Co's Cantay Depositories furniture warehouse was designed by Tollit and built in 1901. Behind its decorative gabled red brick facade, Cantay Depositories has a steel frame and iron columns cast by William Lucy's Eagle Ironworks in Jericho, Oxford. As a warehouse the building had of storage space and was segregated into sections by armoured, fire-proof doors that would close automatically in the event of fire. Cantay House is now Oxford Conference Centre, a nightclub, and a retail store.
Marmalade factory
From 1903 until after the Second World WarFrank Cooper's Oxford Marmalade was made at a factory at 27 Park End Street next to Victoria Buildings. In the sixties and seventies the building was used as offices by various sections of Oxforshire County Council. The former factory is now a listed building. It is now called "The Jam Factory" and houses an arts centre, restaurant, and bar. "The Jam Factory" also houses Guardian Award-winning charity, "My Life My Choice" run by and for people with learning disabilities.
Motor trade
From the end of the First World War a number of car and motorcycle traders had premises in Park End Street. They included King's Motors and Hartwell's, both of which were founded in Oxford in 1919, and Leyton's, which was taken over by King's but remained a separate subsidiary. By 1930 Howard King had premises in Park End Street with showroom space for 100 motorcycles. In 1934 King's had larger premises built at 15 Park End Street with showroom space for 500 motorcycles. The 1934 showroom is a two-storey Art Deco building whose facade is of yellow Bath Stoneashlar to match the Royal Oxford Hotelnext door. The bespoke etched glass panels depicting 30's motoring scenes which were above Kings main showroom windows were saved and are now on display in Bealieu Motor Museum. H.F. Temple was another motorcycle dealer in the 1940s/50s; their premises were situated at 46 Park End Street and also 69 High Street, St Thomas, Oxford. Temples was the main Oxford supplier for the BSA C11G and C12 and is listed in the 1956 BSA C12 Owners handbook as being the only BSA dealer in the city*.. Eyles and Coxeter was another motor dealer in Park End Street in the sixties, they were sited alongside Lower Fisher Row, currently the site of Sushimania, their workshops stretched way down alongside Lower Fisher Row, in the showroom alongside, catering for the 'county' set, they sold Rover, Jaguar, Land Rover and Rice horse boxes. All but one of the motor traders have now moved to premises further from central Oxford. Hartwell's former premises are now a branch of Office Outlet, formerly Staples Inc. Only King's former premises remain in the motor trade: it is now a branch of Kwik-Fit.