PSCA (gene)
Prostate stem cell antigen is a protein that in humans is encoded by the PSCA gene.
This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene has a nonsynonymous nucleotide polymorphism at its start codon.This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas.
