Obaid Siddiqi


Obaid Siddiqi FRS was an Indian National Research Professor and the Founder-Director of the Tata Institute of Fundamental Research National Center for Biological Sciences. He made seminal contributions to the field of behavioural neurogenetics using the genetics and neurobiology of Drosophila.

Early life and education

Obaid Siddiqi was born in 1932 in Basti district of Uttar Pradesh. He received his early education at Aligarh Muslim University where he completed
his M.Sc. He completed his Ph.D. at the University of Glasgow, under the supervision of Guido Pontecorvo. He carried out his post doctoral research at the Cold Spring Harbor Laboratory, University of Pennsylvania, and the MRC Laboratory at Cambridge. He was invited by Homi Bhabha to set up the molecular biology unit at the Tata Institute of Fundamental Research in Bombay in 1962. Thirty years later, he became the founding director of the TIFR National Center for Biological Sciences in Bangalore, where he would continue his research into his final days of life.

Research

Siddiqi's studies in the field of neurogenetics unravelled the link between genes, behaviour and the brain. In the 1970s, his work with Seymour Benzer at Caltech led to the discovery of temperature-sensitive paralytic Drosophila mutants and the generation and transmission of neural signals. This heralded the dawn of the field of neurogenetics.
At TIFR, Siddiqi and his graduate student, Veronica Rodrigues, isolated and characterized the first collection of mutants with defects in smell and taste in Drosophila. Siddiqi's work in neurogenetics led to the foundational advances in understanding how taste and smell are detected and encoded in the brain.

Awards and honours

Siddiqi died on 26 July 2013 in Bangalore following a freak road accident on 21 July 2013 which caused severe damage to the brain. He is survived by his wife Asiya, sons Imran and Kaleem, and daughters Yumna and Diba.

Selected publications