ONIOM
The ONIOM is a computational approach developed by Morokuma and co-workers. ONIOM is the hybrid method that enables different ab initio or semi-empirical methods to be applied to different parts of a molecule/system and combined to produce reliable geometry and energy at reduced computational time.
ONIOM computational approach was found particularly useful for biomolecular systems as well as for transition metal complexes and catalysts.Codes that support ONIOM
