OCRL
Inositol polyphosphate 5-phosphatase OCRL-1, also known as Lowe oculocerebrorenal syndrome protein, is an enzyme encoded by the OCRL gene located on the X chromosome in humans.
This gene encodes a phosphatase enzyme involved in actin polymerization, and is found in the trans-Golgi network.
Mutation in this gene are associated with oculocerebrorenal syndrome and also with Dent's disease.
