The professional wrestling matches at No Way Out featured professional wrestlers performing as characters in scripted events pre-determined by the hosting promotion, WWE. Storylines between the characters played out on WWE's primary television programs, Raw and SmackDown. The main event of the pay-per-view involves John Cena and Big Show. On the May 14 edition of Raw, the general manager of Raw and SmackDown John Laurinaitis fired Big Show for making fun of his voice. At Over the Limit, just before John Cena would defeat Laurinaitis, Big Show turned heel and used his WMD finisher to incapacitate Cena, allowing Laurinaitis to pin Cena and keep his job as General Manager of Raw and SmackDown. The next night on Raw, Laurinaitis revealed that he gave Big Show back his job, complete with an ironclad contract with a bonus on the condition that he would take out Cena as Show was exempt from the "no interference" stipulation for the match. Show stated that he only helped Laurinaitis when he didn't receive any sympathy from the other Superstars, and because of his ironclad contract, started attacking every superstar on the WWE roster in revenge. Laurinaitis would soon book a match between Cena and Big Show inside a steel cage for the pay-per-view. On the June 11 edition of Raw, Mr. McMahon returned to evaluate Laurinaitis's job, but was interrupted by the Big Show, at which point Mr. McMahon announced that if Big Show lost, Laurinaitis would be fired, at which point the Big Show knocked out Mr. McMahon with the WMD after Cena ducked. On the June 15 episode of SmackDown, Laurinaitis announced the stipulation if Cena lost, he would be fired, at which point Cena knocked Laurinaitis out. The main event of SmackDown was originally Sheamus defending his World Heavyweight Championship against Alberto Del Rio. Following a successful title defense by Sheamus against Del Rio, Randy Orton and Chris Jericho at Over the Limit, Del Rio, Orton and Kane competed in a triple threat match on the May 25 edition of SmackDown to earn a title match against Sheamus at No Way Out, which Del Rio won. However, Del Rio was pulled from the match following a concussion during the June 8 episode of SmackDown. On the June 11 edition of Raw, Dolph Ziggler defeated Christian, Jack Swagger and The Great Khali in a fatal-four way elimination match to become the new number one contender for the World Heavyweight Championship. The main event of Raw involved the WWE ChampionCM Punk defending his title in a Triple Threat match against Daniel Bryan and Kane. On the May 18 edition of SmackDown, Punk was put in a match against Kane, where Bryan was in commentary observing the match. Bryan would run interference by attacking Kane with a steel chair and making it look like Punk did it, causing Kane to attack Punk with the chair. On the May 21 edition of Raw, Bryan, who demanded a rematch due to Punk tapping out moments after scoring the pin during their WWE Championship match at Over the Limit, was facing off against Kane, set up by Punk in which the situation nearly reversed itself. Afterwards, Kane would start attacking both indiscriminately after being a pawn in each of their plans. On the June 1 episode of SmackDown, which involved Punk defending the WWE Championship against Kane, Bryan would interfere in the match, attacking both once more, only for Kane to chokeslam both Bryan and Punk. Afterwards, John Laurinaitis came out to announce a triple threat match involving Punk, Bryan and Kane for the WWE Championship at No Way Out.
Event
Pre-show
The pre-show featured Brodus Clay defeating David Otunga by countout.
Preliminary matches
The event opened with Sheamus defending the World Heavyweight Championship against Dolph Ziggler. In the end, Ziggler applied a Sleeper Hold but Sheamus countered into White Noise on Ziggler. Sheamus executed a Brogue Kick on Ziggler to retain the title. Next, United States ChampionSantino Marella faced Ricardo Rodriguez in a Tuxedo match. Marella won by stripping Rodriguez down to his underwear. After that, Christian defended the WWE Intercontinental Championship against Cody Rhodes. The match ended when Rhodes attempted a Beautiful Disaster Kick but Christian avoided and executed a Spear on Rhodes to retain the title. In the fourth match, The Prime Time Players faced Primo & Epico, The Usos, and Tyson Kidd and Justin Gabriel in a Fatal 4-Way Tag team match to determine the #1 contenders to the WWE Tag Team Championship. Young executed a Gut Check on Primo for the victory. Next, Layla defended the WWE Divas Championship against Beth Phoenix. Layla executed a Neckbreaker on Phoenix for the victory. After that, Sin Cara faced Hunico. Sin Cara executed a Tilt-A-Whirl Headscissors Takedown on Hunico for the victory. In the seventh match, CM Punk defended the WWE Championship against Daniel Bryan and Kane. During the match, Bryan applied the Yes Lock on Punk but Punk escaped the hold and executed a GTS on Bryan. Punk pinned Bryan but Kane pulled Bryan out of the ring, voiding the pinfall. Kane attempted a Chokeslam on Punk but Punk countered into a DDT on Kane for a near-fall. Punk executed a Diving Elbow Drop on Kane for a near-fall. Kane executed a Chokeslam on Punk for a near-fall. The match ended when Kane accidentally collided with AJ Lee, allowing Punk to execute the GTS on Kane to retain the title. In the penultimate match, Ryback faced Dan Delaney and Rob Grimes in a Handicap match. Ryback executed a Shell Shocked on Delaney and Grimes simultaneously for the victory.
Main event
In the main event, John Cena faced Big Show inside a Steel Cage. The stipulation of the match was that if Big Show won, John Laurinaitis would fire Cena, but if Cena won, Mr. McMahon would fire Laurinaitis. Big Show dominated the match in the early going, stopping Cena from escaping multiple times. Cena nearly escaped through the door, but Laurinaitis pushed Mr. McMahon into the door, which struck Cena. Show then executed a Chokeslam on Cena for a near-fall. Show then inadvertently attacked the referee with a WMD after Cena ducked. Show then executed a second WMD on Cena and attempted to walk out the door, but was stopped by Brodus Clay, wielding a steel chair. Show then attempted to climb out over the top, but numerous superstars from Zack Ryder to Kofi Kingston tried to knock Show off the top of the cage. Kingston succeeded, temporarily stopping Show. Cena tried to escape through the door, but Show stopped him. Cena then executed an Attitude Adjustment on Show and climbed to the top of the cage, but was stopped by Laurinaitis, wielding his crutches. Clay restrained Laurinaitis, allowing Cena to climb out of the cage for the win before Show could drag himself through the door. McMahon then fired Laurinaitis and Cena put Laurinaitis through the Spanish announcers' table with an Attitude Adjustment as the event ended.
Reception
The event received 194,000 buys, up from last year's Capitol Punishment pay-per-view of 170,000.