NAD(+)—diphthamide ADP-ribosyltransferase
In enzymology, a NAD+-diphthamide ADP-ribosyltransferase is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are NAD+ and peptide diphthamide, whereas its two products are nicotinamide and peptide N-diphthamide.
This enzyme belongs to the family of glycosyltransferases, to be specific, the pentosyltransferases. The systematic name of this enzyme class is NAD+:peptide-diphthamide N-transferase. Other names in common use include ADP-ribosyltransferase, monotransferase, and NAD-diphthamide ADP-ribosyltransferase.As of late 2007, 15 structures have been solved for this class of enzymes, with PDB accession codes,,,,,,,,,,,,,, and.
