At Michigan, he served as offensive line coach from 1992 to 1996. In 1997, he was promoted to offensive coordinator. During DeBord's first year as offensive coordinator in 1997, Michigan won their first national championship since 1948.
DeBord was hired as the head football coach at Central Michigan by athletic director Herb Deromedi in 2000. He would go on to post a 12–34 record, resigning after the 2003 season. DeBord never won more than four games in a season in his time at Central Michigan.
Assistant coach
Return to Michigan
DeBord rejoined the Wolverines in 2004 as special teams and recruiting coordinator for head coach Lloyd Carr, taking over the role filled by the retiring Bobby Morrison. DeBord served in that capacity for two seasons before succeeding Terry Malone as offensive coordinator and tight ends coach in 2006. Malone had previously replaced DeBord when DeBord took the head coaching job at Central Michigan in 2000. DeBord was a candidate for the head coaching position at Michigan following the retirement of Lloyd Carr in 2007. The job ultimately went to Rich Rodriguez, who fired all Michigan assistant coaches except running backs coachFred Jackson. As the offensive coordinator at Michigan, DeBord posted a 52–11 regular season record and a post season record of 4–1.
NFL
On March 5, 2008, the Seattle Seahawks announced that DeBord had been hired as the assistant offensive line coach. DeBord was promoted to tight end coach for the 2009 season. On February 2, 2010, the Chicago Bears announced DeBord as their new tight ends coach, after coming to terms for the 2010 season. DeBord was dismissed by new head coach Marc Trestman on January 17, 2013.
Tennessee
On February 5, 2015, DeBord was hired by Tennessee head coach Butch Jones as offensive coordinator, replacing Mike Bajakian, who left to become quarterbacks coach for the Tampa Bay Buccaneers. Jones had previously worked under DeBord as an assistant coach at Central Michigan. On January 3, 2017, it was announced that DeBord would be leaving Tennessee to become the offensive coordinator for Indiana.
Indiana
On January 4, 2017, Indiana head coach Tom Allen hired DeBord as offensive coordinator, replacing Kevin Johns, who departed the position for offensive coordinator and quarterbacks coach with the Western Michigan Broncos. On December 30, 2018, DeBord announced his retirement from football.
San Diego Fleet
In January 2019, San Diego Fleet offensive coordinator Jon Kitna departed the team to become quarterbacks coach of the Dallas Cowboys. To take his place, the Fleet hired DeBord, reuniting him with Fleet head coach and former Bears colleague Mike Martz.
Third stint at Michigan
DeBord rejoined the Michigan football team on March 4, 2020 as an offensive analyst under head coach Jim Harbaugh.
Sports administration
On February 1, 2013, DeBord was hired by Michigan athletic director Dave Brandon to be the sports administrator for the school's Olympic sports teams. In this role he works with the field hockey, men's and women's cross country, men's and women's gymnastics, men's and women's track and field, and men's and women's tennis programs.