Metharbital

Metharbital was patented in 1905 by Emil Fischer working for Merck. It was marketed as Gemonil by Abbott Laboratories. It is a barbiturate anticonvulsant, used in the treatment of epilepsy. It has similar properties to phenobarbital.

History

Metharbital can be synthesized from 2,2-diethylmalonic acid and O-methylisourea.

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