She was born in Beirut, the capital of Lebanon, her father was a Popular Front for the Liberation of Palestine guerilla leader and her mother was the Japanese Red Army member Fusako Shigenobu. After three Japanese volunteers for the Popular Front for the Liberation of Palestine PFLP External Operations executed an attack on Israel's Lod Airport on 30 May 1972, PFLP leaders and other Japanese volunteers became targets for Israel's assassinations. In retaliation for the attack, PFLP's spokesman Ghassan Kanafani was killed on July 8, 1972, by the Israeli Intelligence AgencyMossad in a car bomb. Mei's mother became wanted by the INTERPOL in 1974 after the French embassy hostage-taking in Hague in which she was thought to be involved, so Mei had to move frequently and used aliases to evade reprisals by her mother's enemies. Mei Shigenobu lived some of her childhood years in Palestinian refugee camps in Lebanon; Fusako Shigenobu was absent for months at a time and Mei was raised in those periods by her mother's comrades in the Japanese Red Army and Arab friends and supporters; while her birth father was killed sometime during her childhood. She had her early education in several schools in Lebanon and in other countries she refuses to name. She studied journalism at the Lebanese University as well as going to the American University of Beirut in Lebanon for her tertiary education where she continued her graduate studies in International Relations. During those years, she learned to speak fluent Arabic and English, but hid her knowledge of Japanese, fearing that if her identity as Fusako Shigenobu's daughter were to become known publicly, her mother might be captured. Though she was not a citizen of any country until March 2001, when she received Japanese citizenship.
She came out of hiding after her mother was captured in Osaka, and visited Japan for the first time in April 2001, making her the first child of a Red Army member to return to Japan in five years. She was the subject of some controversy in December 2001 when she gave a talk at a public school in Kanagawa Prefecture about Arab culture and food at the invitation of a teacher there; the Israeli embassy in Tokyo sent a complaint to the school, describing her discussion as conveying "blatant, biased political" anti-Israeli sentiments. She then began working as an English teacher in a cram school in Tokyo. Japanese lawyers, scholars, journalists, writers and activists responded by signing a protest petition against the Israeli embassy and government saying that Mei was now a Japanese citizen and had the right to freedom of speech in Japan. Mei later became an anchor on Japanese cable television channel Asahi Newstar's one-hour live political programme News no Shinsō. She is currently MBC's Tokyo correspondent, reporting in Arabic about Japan. She earned her PhD degree in Media Studies from Doshisha University in 2011, doing research on the development of Arabic media, and the effect of satellite channels on Arab societies. Mei Shigenobu is a supporter of Palestinian statehood and a critic of Israel. In contrast to Bettina's disavowal, shown in Children of the Revolution, she views her mother's actions with pride, to the point of stating that she considers her a role model, merely repeating, as her mother, that those were different times, as she mentioned to the Standard, "there were no means of gaining media attention", and with today's media and communication, other venues prove far more effective. She attempted to justify the group's terrorist activities by saying that in the 1970s–1980s people had very different "moral values", different "sensibilities and ways of thinking", implying that her mother's sentence should be rendered invalid and echoing her mother's claim that since the criminal acts carried out had had political aims, she should not be convicted but rather offered a "political way out".
Mei Shigenobu appears in Nobuyuki Oura's November 2006 movie 9/11-8/15 Japan Pack Suicide. Mei also appears in Documentary on Zunou Keisatsu, a documentary featuring the life of the Japanese Rock band "Zunou Keisatu" and its lead singer PANTA. In 2010, Mei costarred in the fictional Japanese movie on figure skatingCoach as a sports journalist. In 2010, Mei Shigenobu and her mother Fusako Shigenobu were featured in Shane O'Sullivan's documentary filmChildren of the Revolution, which premiered at the International Documentary Festival Amsterdam. In 2011, Mei Shigenobu was featured in Eric Baudelaire's experimental movie The Anabasis of May and Fusako Shigenobu, Masao Adachi, and 27 years without Images along with filmmaker and Japanese Red Army member Masao Adachi, which was entered at the 22nd Marseilles International Film Festival. On 10 September 2012, Mei Shigenobu appeared as a guest in the program Free word on Al Mayadeen Channel hosted by George Galloway.
