The structure of the film consists of several subplots which all revolve around an intertwined cast of characters. The film begins by introducing Richard, a shoe salesman and recently separated father of two. After being thrown out by his wife Pam, he gets an apartment of his own to share with his children, Peter and Robby. He meets Christine, a senior-cab driver and amateur video artist, while she takes her client to shop for shoes, and the two develop a fledgling romantic relationship. Robby, six years old, and his 14-year-old brother, Peter, have a joint online chat which he later depicts in another chat session as "))<> and Rebecca, develop a playful relationship with a much older neighbor Andrew who works in the shoe store with Richard. He does not say much, but he keeps leaving signs on his window about what he would do to each of them. As a result of this relationship, Heather and Rebecca ask Peter if they can practice oral sex on him, so that he can tell them which of the two does it better; so they do. He says both were exactly the same. The daughter of a neighbor peeks in the window, sees what is happening, and quickly leaves. Heather and Rebecca later come to the neighbor's house intending to have sex with him as practice, but he appears afraid when he sees them through his window and he pretends not to be home. Meanwhile, Christine's work is rejected by a contemporary art museum, but then later accepted by the curator, who turns out to be the woman who was instant messaging with the brothers. The plots come togetherin the end, with Peter developing a friendship with the daughter of a neighbor, having been introduced to the hope chest that she has, Christine and Richard displaying a show of mutual acceptance of their attraction to each other, and, as a final plot device, Robby finding that the noise he had awoken to early every morning was that of an early-rising businessman tapping a quarter on a street sign pole. When asked why he is doing it, he stops and turns around, saying "just passing the time", and gives Robby the quarter. When his bus drives away and Robby tries it out himself, the sun heightens with each tap, time literally passing as he does it.
The film received largely positive reviews; it currently holds an 82% 'fresh' rating on Rotten Tomatoes, with the consensus stating, "Miranda July's debut feature is a charmingly offbeat and observant film about people looking for love." On Metacritic, Me and You holds a 76, indicating "Generally favorable reviews". The film won the Caméra d'Or at the Cannes Film Festival. Roger Ebert cited it as the fifth best film of the decade. Peter Bradshaw for The Guardian, however, stated in a negative review of this film: "It feels as if watching this will earn you credits on an American college discourse on emotional correctness."
