His taxonomic contributions include categorizing and naming cichlids and pupfish, revising cichlid genera Herichthys and establishing Nosferatu. He also co-authored with renowned gastropod expert, , Research Zoologist and Curator of Mollusca at the Smithsonian, and his team, on cochliopid snails from thermal springs in northern Mexico. His work includes:
De La Maza-Benignos, M. & Lozano-Vilano, M.d.L. 2013. Description of three new species of the genus Herichthys from eastern Mexico, with redescription of H. labridens, H. steindachneri, and H. pantostictus. Zootaxa, 3734 : 101–129.
De la Maza-Benignos. M., C.P. Ornelas-García, Ma. de L. Lozano-Vilano, M.E. García Ramírez, and I. Doadrio, 2014. Phylogeographic analysis of genus Herichthys, with descriptions of Nosferatu new genus and H. tepehua n. sp. 2014. hydrobiologia.
De la Maza-Benignos, M. and L. Vela-Valladares. 2009. "Cyprinodon julimes sp. nov". In: . Alianza WWF - FGRA y Gobierno del Estado de Chihuahua.
Hershler, R., J. J. Landye, L. Hsiu-Ping, M. De la Maza–Benignos, P. Ornelas & E.W. Carson. 2014. New species and records of Chihuahuan Desert springsnails, with a new combination for Tryonia brunei. Western North American Naturalist 74: 47–65.
Conservation work
From 2006-2011, De la Maza-Benignos led the design and directed the implementation of the , which involved working with the governments of the US and Mexico, local NGOs and communities along the Rio Conchos, one of the primary tributaries of the Rio Grande/Río Bravo. The project focused on aspects of ecosystem, source water protection, and restoration, efficient water use, engaging in participatory platforms, improved water governance and policy development, public awareness and education. It provided training in the implementation of environmental flows, soil and water conservation techniques, biodiversity conservation, development of community action plans, and distribution of educational materials comprising basic social, economic and environmental information. Work centered on building capacity for freshwater and wildlife management, including large mammals and conserving the native Aparique trout and the Julimes pupfish, as part of the WWF-TCCC global partnership.
Legal and policy work
Dr. De la Maza led the efforts that brought about, in 2014, the first concession of surface waters for “environmental use” in Mexico, within Cuatrociénegas' Area for Protection of Flora and Fauna, established by the National Commission for Natural Protected Areas in the state of Coahuila. "By this act, Mexico´s National Water Commission established the necessary legal mechanisms to ensure the security and legal certainty of water resources needed to protect priority ecosystems, thereby supporting the healthy environment to which every person in Mexico is entitled for his/her development and well-being under article 4 of the Mexican Constitution, while also promoting sustainable development of water resources.”