Borella started her professional MMA career in 2014 and fought primarily in the European circuit. Borella joined Invicta Fighting Championships prior to signing with the UFC in 2017.
Borella made her UFC debut on October 7, 2017. Borella faced Kalindra Faria at UFC 216 in Las Vegas, United States, replacing Andrea Lee. She won the fight via a submission. Borella next faced Katlyn Chookagian on January 27, 2018 at UFC on Fox 27. She lost the fight via a unanimous decision. Borella faced Taila Santos on February 2, 2019 at. She won the fight by split decision. Borella faced Lauren Murphy on August 3, 2019 at UFC on ESPN 5. She lost the fight via TKO in the third round. Borella faced Montana De La Rosa on February 15, 2020 at UFC Fight Night 167. She lost the fight via unanimous decision. Borella faced Cortney Casey on May 16, 2020 at. She lost the bout in the first round via submission through an armbar. Borella was expected to face promotional newcomer Miranda Maverick on June 27, 2020 at. However, Maverick was forced to pull out due to injury. It is unclear at the moment if a replacement would be sought by UFC officials.
Suspension for 26 years for distributing and selling of cocaine
Borella was arrested by Italian authorities under "Operation Flanker" for distributing and selling cocaine and cannabis at sporting venues, an operation conducted by the Investigative Unit of the Carabinieri of Piacenza in Emilia and Lombardy. Borella entered into plea deals in 2012 along with 33 defendants where punishments were of up to one and four years in prison. She spent a period in prison and later under house arrest for the incident. Borella was also suspended by the National Anti Doping Agency of Italy for 15 years for distributing and selling prohibited drugs. The same agency then added an additional 11-year suspension, for a total of 26 years, until 2044, for use of Italian sporting facilities while serving a suspension under the Italian Anti Doping Code article 4.12.3. It was reported on October 19, 2018, that Borella was free to compete in the UFC as the United States Anti-Doping Agency UFC anti-doping program does not consider Borella's criminal activity a violation, as it was unrelated to performance enhancement. Borella is scheduled to face Mayra Bueno Silva on September 5, 2020 at UFC Fight Night 177.